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- Table of Contents
27 Citations 18 Q&As
26 Citations 15 Q&As
9 Citations 16 Q&As
41 Citations 16 Q&As
7 Citations 15 Q&As
2 Citations
Facts about Collagen alpha-1(III) chain.
Is the significant ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12. .
Human | |
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Gene Name: | COL3A1 |
Uniprot: | P02461 |
Entrez: | 1281 |
Belongs to: |
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fibrillar collagen family |
alpha1 (III) collagen; COL3A1; Collagen 3; collagen alpha-1(III) chain; Collagen III alpha 1; collagen, fetal; collagen, type III, alpha 1; Collagen-3; EDS4A; Ehlers-Danlos syndrome type IV, autosomal dominant; FLJ34534
Mass (kDA):
138.564 kDA
Human | |
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Location: | 2q32.2 |
Sequence: | 2; NC_000002.12 (188974373..189012746) |
Secreted, extracellular space, extracellular matrix.
PMID: 2764886 by Ala-Kokko L., et al. Structure of cDNA clones coding for the entire prepro alpha 1 (III) chain of human type III procollagen. Differences in protein structure from type I procollagen and conservation of codon preferences.
PMID: 11566270 by Valkkila M., et al. Genomic organization of the human COL3A1 and COL5A2 genes: COL5A2 has evolved differently than the other minor fibrillar collagen genes.
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