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COL13A1 Antibodies
AND COL13A1 ELISA kits, COL13A1 Proteins
Many biological assays use antibodies to detect COL13A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with COL13A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop COL13A1 antibodies...
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COL13A1 Overview
Facts about Collagen alpha-1(XIII) chain.
Collagen alpha-1(XIII) chain (COL13A1)
Involved in cell-matrix and cell-cell adhesion interactions that are required for normal development. May participate in the linkage between muscle fiber and basement membrane.
May play a role in endochondral ossification of bone and branching morphogenesis of lung. Binds heparin.
Gene Information
| Human | |
|---|---|
| Gene Name: | COL13A1 |
| Uniprot: | Q5TAT6 |
| Entrez: | 1305 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
COL13A1; collagen alpha-1(XIII) chain; Collagen XIII alpha 1; collagen, type XIII, alpha 1; FLJ42485
Molecular Weight
Mass (kDA):
69.95 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10q22.1 |
| Sequence: | 10; NC_000010.11 (69801835..69959144) |
Tissue Specificity
Widely expressed in both fetal and adult ocular tissues (at protein level). In the eye, expression is accentuated in the ciliary muscle, optic nerve and the neural retina. In early placenta, localized to fibroblastoid stromal cells of the placental villi, to endothelial cells of developing capillaries and to cells of the cytotrophoblastic columns. Also detected in large decidual cells of the decidual membrane and to stromal cells of the gestational endometrium, but not in the epithelial cells in the endometrial glands. Isoform 10: Expressed in muscle (PubMed:26626625).
Subcellular Localizations
Cell membrane; Single-pass type II membrane protein. Cell junction, synapse, postsynaptic cell membrane.
Diseases
- Malignant Neoplasms
- Tissue Adhesions
- Inflammation
- Neoplasms
- Liver Diseases
- Neoplasms, Radiation-induced
- Myasthenic Syndromes, Congenital
- Malignant Tumor Of Colon
- Carcinoma, Papillary
- Overlap Connective Tissue Disease
- Degenerative Polyarthritis
- Myopathy
Pathways
- Cell Adhesion
- Metaphase
- Interphase
- Immune Response
- Response To Fenofibrate
- Localization
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COL13A1
bosterbio.com/bosterbio-gene-info-cards/COL13A1
References
PMID: 11013208 by Snellman A., et al. A short sequence in the N-terminal region is required for the trimerization of type XIII collagen and is conserved in other collagenous transmembrane proteins.
PMID: 1698771 by Pihlajaniemi T., et al. The alpha 1 chain of type XIII collagen consists of three collagenous and four noncollagenous domains, and its primary transcript undergoes complex alternative splicing.