COL11A1 Antibodies

AND COL11A1 ELISA kits, COL11A1 Proteins

Many biological assays use antibodies to detect COL11A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with COL11A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop COL11A1 antibodies...

We validate the specificity of these antibodies to COL11A1 by testing them on tissues known to express COL11A1 positively and negatively. Browse below to find the COL11A1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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COL11A1 Infographic by Boster Bio

All COL11A1 Products

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Product

Figures

Specificity

Applications

Price

Anti-Collagen XI alpha COL11A1 Antibody

5 Q&As

Human, Mouse

$360
Cat # A02909
100 µl

Collagen XI alpha1 Colorimetric Cell-Based ELISA Kit

Human, Mouse

ELISA

$480
Cat # EKC1132
1 kit, containing one 96-well plate and all necessary reagents

Anti-COL11A1 (G610) Antibody

Human, Mouse

IHC

$405
Cat # A02909-1
100ul

Anti-Collagen XI alpha COL11A1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A02909-2
100ul

Anti-COL11A1 Rabbit Monoclonal Antibody

Human

$370
Cat # M02909
100 μl/vial

COL11A1 Overview

Facts about Collagen alpha-1(XI) chain.

COL11A1 3D structure. Source: alphafold

Collagen alpha-1(XI) chain (COL11A1)

May play an essential role in fibrillogenesis by controlling lateral growth of collagen II fibrils. .

Gene Information

Human
Gene Name:	COL11A1
Uniprot:	P12107
Entrez:	1301

Family

Belongs to:

fibrillar collagen family

Alternative Names

alpha-1 polypeptide; COLL6; collagen, type XI, alpha 1

Molecular Weight

Mass (kDA):
181.065 kDA

Genomic Context


Human

Location:	1p21.1
Sequence:	1; NC_000001.11 (102876467..103108580, complement)

Tissue Specificity

Cartilage, placenta and some tumor or virally transformed cell lines. Isoforms using exon IIA or IIB are found in the cartilage while isoforms using only exon IIB are found in the tendon.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

Stickler Syndrome (disorder)
Myopia
Neoplasms
Malignant Neoplasms
Degenerative Polyarthritis
Dysplasia
Osteochondrodysplasias
Sensorineural Hearing Loss (disorder)
Retinal Detachment
Marshall Syndrome
Eye Diseases, Hereditary
Severe Myopia

Arthropathy
Cleft Palate
Connective Tissue Diseases
Tissue Adhesions
Neoplasm Metastasis
Carcinoma
Complete Hearing Loss

Pathways

Pathogenesis
Translation
Cell Adhesion
Immune Response
Ossification
Cell Cycle
Localization
Cell Migration
Osteoblast Differentiation
Aging
Lung Development
Proteolysis
Tropism

Chondrocyte Differentiation
Tendon Development
Cell Maturation
Cartilage Development
Mrna Splicing
Cell Motility
Cell Differentiation

PTMs

Sulphation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COL11A1

References

PMID: 1690726 by Yoshioka H., et al. Pro-alpha 1(XI) collagen. Structure of the amino-terminal propeptide and expression of the gene in tumor cell lines.

PMID: 10486316 by Annunen S., et al. Splicing mutations of 54-bp exons in the COL11A1 gene cause Marshall syndrome, but other mutations cause overlapping Marshall/Stickler phenotypes.