COL11A2 Antibodies

AND COL11A2 ELISA kits, COL11A2 Proteins

Many biological assays use antibodies to detect COL11A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with COL11A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop COL11A2 antibodies...

We validate the specificity of these antibodies to COL11A2 by testing them on tissues known to express COL11A2 positively and negatively. Browse below to find the COL11A2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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COL11A2 Infographic by Boster Bio

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Collagen XI alpha 2 (COL11A2) (NM_080680) Human Over-expression Lysate

Human

$960
Cat # LS001302
100 µg

COL11A2 Overview

Facts about Collagen alpha-2(XI) chain.

COL11A2 3D structure. Source: alphafold

Collagen alpha-2(XI) chain (COL11A2)

May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. .

Gene Information

Human
Gene Name:	COL11A2
Uniprot:	P13942
Entrez:	1302

Family

Belongs to:

fibrillar collagen family

Alternative Names

collagen alpha-2(XI) chain; collagen, type XI, alpha 2; DFNA13; DFNB53; HKE5; PARP; pro-a2 chain of collagen type XI; STL3

Molecular Weight

Mass (kDA):
171.791 kDA

Genomic Context


Human

Location:	6p21.32
Sequence:	6; NC_000006.12 (33162692..33193009, complement)

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

Malignant Neoplasms
Neoplasms
Stickler Syndrome (disorder)
Dysplasia
Sensorineural Hearing Loss (disorder)
Osteochondrodysplasias
Carcinoma
Degenerative Polyarthritis
Cleft Palate
Complete Hearing Loss
Leukemia
Malignant Tumor Of Colon
Colonic Neoplasms

Arthropathy
Inflammation
Malignant Neoplasm Of Breast
Intervertebral Disc Degeneration
Ossification Of Posterior Longitudinal Ligament
Myopia
Otospondylomegaepiphyseal Dysplasia

Interacting Proteins

DDR2

Pathways

Cell Death
Cell Proliferation
Induction Of Apoptosis
Ossification
Cell Cycle
Cell Cycle Arrest
Pathogenesis
Chondrocyte Differentiation
Localization
Dna Repair
Regulation Of Gene Expression
Programmed Cell Death
Aging

Translation
Drug Resistance
Cell Growth
Apoptotic Process
Sex Determination
Endochondral Ossification
Immune Response

PTMs

Cleavage
Phosphorylation
Ubiquitination
Deacetylation
Methylation
Dephosphorylation

Acetylation
Oxidation
Sumoylation
Deamination
Citrullination
Reduction

Palmitoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COL11A2

References

PMID: 7559422 by Vuoristo M.M., et al. The human COL11A2 gene structure indicates that the gene has not evolved with the genes for the major fibrillar collagens.

PMID: 8838804 by Lui V.C., et al. The human alpha 2(XI) collagen gene (COL11A2): completion of coding information, identification of the promoter sequence, and precise localization within the major histocompatibility complex reveal overlap with the KE5 gene.