Centlein Antibodies

AND CNTLN ELISA kits, Centlein Proteins

Many biological assays use antibodies to detect Centlein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Centlein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Centlein antibodies...

We validate the specificity of these antibodies to Centlein by testing them on tissues known to express CNTLN positively and negatively. Browse below to find the CNTLN antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CNTLN Infographic by Boster Bio

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CNTLN Overview

Facts about Centlein.

CNTLN 3D structure. Source: alphafold

Centlein (CNTLN)

Required for centrosome cohesion and recruitment of CEP68 to centrosomes. .

Gene Information

Human
Gene Name:	CNTLN
Uniprot:	Q9NXG0
Entrez:	54875

Family

Belongs to:

No superfamily

Alternative Names

bA340N12.1; C9orf101chromosome 9 open reading frame 101; C9orf39chromosome 9 open reading frame 39; centlein; centlein, centrosomal protein; Centrosomal protein; FLJ20276; FLJ25636; RP11-340N12.1

Molecular Weight

Mass (kDA):
161.571 kDA

Genomic Context


Human

Location:	9p22.2
Sequence:	9; NC_000009.12 (17134991..17510020)

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Colocalizes with gamma-tubulin during interphase and mitosis. Appears to associate with the mother centriole during G1 phase and with daughter centrioles towards G1/S phase (By similarity). Localizes to the proximal ends of the centrioles (PubMed:24554434). Levels are high at interphase centrosomes but are reduced on mitotic spindle poles (PubMed:24554434).

Diseases

Hypertensive Disease
Coronary Heart Disease
Heart Diseases

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CNTLN

References

PMID: 24554434 by Fang G., et al. Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion.