CNMD Antibodies

AND CNMD ELISA kits, CNMD Proteins

Many biological assays use antibodies to detect CNMD, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CNMD in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CNMD antibodies...

We validate the specificity of these antibodies to CNMD by testing them on tissues known to express CNMD positively and negatively. Browse below to find the CNMD antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CNMD Infographic by Boster Bio

All CNMD Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-LECT1 CNMD Antibody

Human, Mouse

IF, ICC, WB

$405
Cat # A32278
100ul

Anti-LECT1 CNMD Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A32278-1
100ul

Human LECT1 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTO75829
Starting from 20ug

LECT1 (CNMD) (NM_007015) Human Over-expression Lysate

Human

$628
Cat # LS011061
100 µg

CNMD Overview

Facts about Leukocyte cell-derived chemotaxin 1.

CNMD 3D structure. Source: alphafold

Leukocyte cell-derived chemotaxin 1 (CNMD)

Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid development of cartilage and vascular invasion before the replacement of cartilage by bone during endochondral bone development.

Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.

Gene Information

Human
Gene Name:	CNMD
Uniprot:	O75829
Entrez:	11061

Family

Belongs to:

chondromodulin-1 family

Alternative Names

Leukocyte cell-derived chemotaxin 1

Molecular Weight

Mass (kDA):
37.102 kDA

Genomic Context


Human

Location:	13q14.3
Sequence:	13; NC_000013.11 (52703264..52739820, complement)

Tissue Specificity

Detected in cartilage and cardiac valves (at protein level). Detected in the laminae fibrosa, spongiosa and ventricularis layers of normal cardiac valves (at protein level). Expression is decreased cardiac valves of patients with valvular heart disease (at protein level). Weakly expressed in chondrosarcoma.

Subcellular Localizations

[Chondromodulin-1]: Secreted, extracellular space, extracellular matrix. Accumulated in the inter-territorial matrix of cartilage.; [Chondrosurfactant protein]: Endomembrane system; Single-pass membrane protein.

PTMs

Cleavage on pair of basic residues

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CNMD

References

PMID: 9731231 by Shukunami C., et al. Expression of cartilage-specific functional matrix chondromodulin-I mRNA in rabbit growth plate chondrocytes and its responsiveness to growth stimuli in vitro.

PMID: 10103018 by Hiraki Y., et al. Molecular cloning of human chondromodulin-I, a cartilage-derived growth modulating factor, and its expression in Chinese hamster ovary cells.