Clathrin heavy chain 2 Antibodies

AND CLTCL1 ELISA kits, Clathrin heavy chain 2 Proteins

Many biological assays use antibodies to detect Clathrin heavy chain 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Clathrin heavy chain 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Clathrin heavy chain 2 antibodies...

We validate the specificity of these antibodies to Clathrin heavy chain 2 by testing them on tissues known to express CLTCL1 positively and negatively. Browse below to find the CLTCL1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CLTCL1 Infographic by Boster Bio

All CLTCL1 Products

Product

Figures

Specificity

Applications

Price

Anti-Clathrin heavy chain 2 CLTCL1 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A09754
100ul

CLTCL1 (NM_007098) Human Over-expression Lysate

Human

$960
Cat # LS008218
100 µg

CLTCL1 Overview

Facts about Clathrin heavy chain 2.

CLTCL1 3D structure. Source: alphafold

Clathrin heavy chain 2 (CLTCL1)

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two distinct adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network (By similarity).

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Gene Information

Human
Gene Name:	CLTCL1
Uniprot:	P53675
Entrez:	8218

Family

Belongs to:

clathrin heavy chain family

Alternative Names

CHC22; Clathrin Heavy Chain 2; clathrin heavy chain on chromosome 22; clathrin, heavy chain-like 1; Clathrin, heavy polypeptide D; CLH-22; CLTCL; CLTCL1; CLTD; heavy polypeptide-like 1

Molecular Weight

Mass (kDA):
187.03 kDA

Genomic Context


Human

Location:	22q11.21
Sequence:	22; NC_000022.11 (19179473..19291719, complement)

Tissue Specificity

Maximal levels in skeletal muscle. High levels in heart and testis. Low expression detected in all other tissues.

Subcellular Localizations

Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic face of coated pits and vesicles.

Diseases

Congenital Heart Defects
Ventricular Septal Defects
Neoplasms
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Tetralogy Of Fallot
Heart Septal Defects
Down Syndrome
Heart Diseases
Trisomy
Stenosis
Trisomy 8
Digeorge Syndrome

Atresia
Malignant Neoplasm Of Breast
Enterovirus Infections
Carcinoma
Carcinoma In Situ
Malignant Neoplasms
Meningeal Neoplasms

Pathways

Endocytosis
Clathrin-mediated Endocytosis
Transport
Mitosis
Pathogenesis
Receptor-mediated Endocytosis
Proteolysis
Metaphase
Localization
Cytokinesis

Regeneration
Cell Cycle
S Phase
Rna Interference
Myoblast Differentiation

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CLTCL1

References

PMID: 8733128 by Sirotkin H., et al. Isolation of a new clathrin heavy chain gene with muscle-specific expression from the region commonly deleted in velo-cardio-facial syndrome.

PMID: 8733129 by Kedra D., et al. Characterization of a second human clathrin heavy chain polypeptide gene (CLH-22) from chromosome 22q11.