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CLCN4 Antibodies

AND CLCN4 ELISA kits, CLCN4 Proteins

Many biological assays use antibodies to detect CLCN4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CLCN4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CLCN4 antibodies...

We validate the specificity of these antibodies to CLCN4 by testing them on tissues known to express CLCN4 positively and negatively. Browse below to find the CLCN4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CLCN4 Infographic by Boster Bio

CLCN4 protein infographic

All CLCN4 Products

Product

Figures

Specificity

Applications

Price

Anti-CLCN4/Clc 4 Antibody

6 Q&As

Human, Mouse, Rat

IF, IHC, WB

$360
Cat # A09156
100 µl

CLCN4 (NM_001830) Human Over-expression Lysate

Human

$960
Cat # LS001183
100 µg

CLCN4 Overview

Facts about H(+)/Cl(-) exchange transporter 4.

CLCN4 3D structure

CLCN4 3D structure. Source: alphafold

H(+)/Cl(-) exchange transporter 4 (CLCN4)

Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons.

.

Gene Information

Human
Gene Name:	CLCN4
Uniprot:	P51793
Entrez:	1183

Gene Information

Family

Belongs to:

chloride channel (TC 2.A.49) family

Family

Alternative Names

chloride channel 4; Chloride channel protein 4; Chloride transporter ClC-4; CLC4; ClC-4; ClC-4A; H(+)/Cl(-) exchange transporter 4; MGC163150

Molecular Weight

Mass (kDA):
84.917 kDA

Molecular Weight

Genomic Context


Human

Location:	Xp22.2
Sequence:	X; NC_000023.11 (10156945..10237660)

Tissue Specificity

Abundant in skeletal muscle and also detectable in brain and heart.

Subcellular Localizations

Early endosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane.

Subcellular Localization

Diseases

Dent's Disease
Kidney Diseases
Liver Neoplasms
Fanconi Syndrome
Nephrolithiasis
Proteinuria Of Undiagnosed Cause
Genetic Diseases, X-linked
Kidney Failure
Albinism, Ocular
Albinism
Neoplasm Metastasis
Microphthalmos
Metastatic Malignant Neoplasm To The Liver

Malignant Tumor Of Colon
Oculocerebrorenal Syndrome
Poisoning Syndrome
Neoplasm Invasiveness
Endometriosis, Site Unspecified
Fibrosis
Malignant Neoplasms

Disease

Pathways

Transport
Localization
Pathogenesis
Secretion
Cell Adhesion
Cell Migration
Gene Silencing
Proton Transport
Osteoblast Differentiation
Anion Transport
Chloride Transport
Male Meiosis
Lung Development

Lung Growth
Membrane Depolarization
Coagulation
Antiport
Amino Acid Transport
Bone Development
Meiosis

Pathways

PTMs

Phosphorylation

Oxidation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CLCN4

References

PMID: 8069296 by van Slegtenhorst M.A., et al. A gene from the Xp22.3 region shares homology with voltage-gated chloride channels.

PMID: 10564087 by Kawasaki M., et al. Identification of an acid-activated Cl- channel from human skeletal muscles.