Chemokine-like factor Antibodies

AND CKLF ELISA kits, Chemokine-like factor Proteins

Many biological assays use antibodies to detect Chemokine-like factor, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Chemokine-like factor in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Chemokine-like factor antibodies...

We validate the specificity of these antibodies to Chemokine-like factor by testing them on tissues known to express CKLF positively and negatively. Browse below to find the CKLF antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CKLF Infographic by Boster Bio

All CKLF Products

Product

Figures

Specificity

Applications

Price

Anti-C32 CKLF Antibody

Human

ELISA, WB

$380
Cat # A04020
100ul

CKLF (NM_181640) Human Over-expression Lysate

Human

$628
Cat # LS051192
100 µg

CKLF Overview

Facts about Chemokine-like factor.

CKLF 3D structure. Source: alphafold

Chemokine-like factor (CKLF)

May play an essential role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10.

Gene Information

Human
Gene Name:	CKLF
Uniprot:	Q9UBR5
Entrez:	51192

Family

Belongs to:

chemokine-like factor family

Alternative Names

C32CKLF2; chemokine-like factor 1; chemokine-like factor 2; chemokine-like factor 3; chemokine-like factor 4; chemokine-like factor; CKLF1; CKLF3; CKLF4; HSPC224; transmembrane proteolipid; UCK-1

Molecular Weight

Mass (kDA):
17.17 kDA

Genomic Context


Human

Location:	16q21
Sequence:	16; NC_000016.10 (66552563..66566287)

Tissue Specificity

Isoform 1, isoform 2, isoform 3 and isoform 4 have highest expression levels in adult spleen, lung, testis, ovary, peripheral blood leukocyte, placenta, pancreas, and in fetal brain, skeletal muscle, thymus and heart. Lower expression levels in adult skeletal muscle, liver, thymus colon, prostate and fetal spleen and liver.

Subcellular Localizations

[Isoform 1]: Secreted.; [Isoform 2]: Membrane; Multi-pass membrane protein.; [Isoform 4]: Membrane; Multi-pass membrane protein.

Diseases

Cholangiocarcinoma
Inflammation
Asthma
Fibrosis
Sclerosis
Acute Myocardial Infarction
Infarction
Myocardial Infarction
Pertussis
Pulmonary Fibrosis
Pneumonia
Cystadenocarcinoma
Neoplasm Metastasis

Dermatomyositis
Lupus Nephritis
Carcinoma
Diffuse Scleroderma
Myopathy
Malignant Neoplasms
Nephritis

Pathways

Chemotaxis
Rna Splicing
Regeneration
Pathogenesis
Localization
Spermatogenesis
Receptor Internalization
Cell Growth
Myoblast Proliferation
Cell Proliferation
Cell Migration
Response To Virus
Defense Response

Cell Maturation
Reverse Transcription
Cell Cycle
Cell Differentiation
Lymphocyte Activation
Secretion
Myoblast Fusion

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CKLF

References

PMID: 11415443 by Han W., et al. Molecular cloning and characterization of chemokine-like factor 1 (CKLF1), a novel human cytokine with unique structure and potential chemotactic activity.

PMID: 16137713 by Wang Y., et al. Chemokine-like factor 1 is a functional ligand for CC chemokine receptor 4 (CCR4).