Cidec Antibodies

AND Cidec ELISA kits, Cidec Proteins

Many biological assays use antibodies to detect Cidec, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cidec in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cidec antibodies...

We validate the specificity of these antibodies to Cidec by testing them on tissues known to express Cidec positively and negatively. Browse below to find the Cidec antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Cidec Infographic by Boster Bio

All Cidec Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

CIDEC Cell Death-Inducing DFFA-Like Effector C Human Recombinant Protein

Human

$250
Cat # PROTQ96AQ7
2ug, 10ug, 1mg

Anti-CIDE-3 CIDEC Antibody

Human

ELISA, IF, IHC

$380
Cat # A03939
100ul

CIDE C (CIDEC) (NM_022094) Human Over-expression Lysate

Human

$628
Cat # LS063924
100 µg

Cidec Overview

Facts about Cell death activator CIDE-3.

Cell death activator CIDE-3 (Cidec)

Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets.

The transfer direction might be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1.

Gene Information

Mouse
Gene Name:	Cidec
Uniprot:	P56198
Entrez:	14311

Family

Belongs to:

No superfamily

Alternative Names

cell death activator CIDE-3; cell death-inducing DFFA-like effector c; Cell death-inducing DFFA-like effector protein C; CIDE-3; CIDEC; CIDEX; Fat-specific protein FSP27 homolog; FLJ20871; FSP27; FSP27fat specific protein 27

Molecular Weight

Mass (kDA):
27.324 kDA

Genomic Context


Mouse

Location:	6\|6 E3
Sequence:	6;

Tissue Specificity

Expressed almost exclusively in adipose tissue, including subcutaneous and epididymal white adipose tissue (at protein level). Although abundantly present in brown adipose tissue at the mRNA level, the protein is almost undetectable in this tissue (PubMed:18654663), or at moderate levels (PubMed:22245780, PubMed:12910269). Expressed in the mammary gland, in stromal adipose tissue, but becomes undetectable at the end of pregnancy and during lactation (at protein level). Expressed at low levels in skeletal muscle and heart.

Diseases

Obesity
Diabetes Mellitus
Insulin Resistance
Steatohepatitis
Steatosis
Metabolic Diseases
Fatty Liver
Diabetes Mellitus, Non-insulin-dependent
Inflammation
Metabolic Syndrome X
Lipodystrophy
Liver Carcinoma
Hyperinsulinism

Acquired Partial Lipodystrophy
Insulin Sensitivity
Autoimmune Reaction
Familial Partial Lipodystrophy
Dyslipidemias
Carcinoma
Neoplasms

Pathways

Cell Death
Lipid Homeostasis
Fatty Acid Oxidation
Glycosylation
Energy Homeostasis
Localization
Lipid Storage
Chromosome Localization
Programmed Cell Death
Mitosis
Immune Response

Release Of Cytochrome C From Mitochondria
Reverse Transcription
Lipid Binding
Cell Growth
Pathogenesis
Oncogenesis

PTMs

Oxidation

Phosphorylation

Research Areas

Apoptosis
Cancer
DNA Repair

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Cidec

References

PMID: 1339452 by Danesch U., et al. Cloning and transcriptional regulation of a novel adipocyte-specific gene, FSP27. CAAT-enhancer-binding protein (C/EBP) and C/EBP-like proteins interact with sequences required for differentiation- dependent expression.

PMID: 12910269 by Zhou Z., et al. Cidea-deficient mice have lean phenotype and are resistant to obesity.