CIB2 Antibodies

AND CIB2 ELISA kits, CIB2 Proteins

Many biological assays use antibodies to detect CIB2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CIB2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CIB2 antibodies...

We validate the specificity of these antibodies to CIB2 by testing them on tissues known to express CIB2 positively and negatively. Browse below to find the CIB2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CIB2 Infographic by Boster Bio

All CIB2 Products

Product

Figures

Specificity

Applications

Price

Anti-CIB2 Antibody

5 Q&As

Human, Mouse, Rat

ELISA, IHC-P, IF (paraffin)

$335
Cat # A08179-1
100ul

Human CIB2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTO75838
Starting from 20ug

CIB2 (NM_006383) Human Over-expression Lysate

Human

$628
Cat # LS010518
100 µg

CIB2 Overview

Facts about Calcium and integrin-binding family member 2.

CIB2 3D structure. Source: alphafold

Calcium and integrin-binding family member 2 (CIB2)

Calcium-binding protein critical for proper photoreceptor cell maintenance and operate. Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release (PubMed:23023331, PubMed:26173970, PubMed:26426422).

May be involved in the mechanotransduction process (By similarity). .

Gene Information

Human
Gene Name:	CIB2
Uniprot:	O75838
Entrez:	10518

Family

Belongs to:

No superfamily

Alternative Names

2810434I23Rik; calcium and integrin binding family member 2; DNA-dependent protein kinase catalytic subunit-interacting protein 2; Kinase-interacting protein 2; KIP 2; KIP2calcium and integrin-binding family member 2

Molecular Weight

Mass (kDA):
21.644 kDA

Genomic Context


Human

Location:	15q25.1
Sequence:	15; NC_000015.10 (78104606..78131976, complement)

Tissue Specificity

Widely expressed (PubMed:23023331).

Subcellular Localizations

Cytoplasm. Cell projection, stereocilium. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. Cell membrane, sarcolemma. Colocalized with ITGA7 at the myotendinous junctions (MTJ) and at the neuromuscular junctions (NMJ) (By similarity). Localizes in the cuticular plate along and at the tip of the stereocilia of vestibular sensory hair cells (PubMed:26173970, PubMed:26426422).

Diseases

Usher Syndrome
Cataract
Complete Hearing Loss
Autistic Disorder
Congenital Muscular Dystrophy (disorder)
Nervousness
Sensorineural Hearing Loss (disorder)
Muscular Dystrophy, Animal

Autism Spectrum Disorders
Dystrophy
Muscular Dystrophy

Pathways

Translation
Localization

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CIB2

References

PMID: 9931475 by Seki N., et al. Structure, expression profile and chromosomal location of an isolog of DNA-PKcs interacting protein (KIP) gene.

PMID: 22779914 by Huang H., et al. Biophysical and structural studies of the human calcium- and integrin-binding protein family: understanding their functional similarities and differences.