CIB1 Antibodies

AND CIB1 ELISA kits, CIB1 Proteins

Many biological assays use antibodies to detect CIB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CIB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CIB1 antibodies...

We validate the specificity of these antibodies to CIB1 by testing them on tissues known to express CIB1 positively and negatively. Browse below to find the CIB1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CIB1 Infographic by Boster Bio

All CIB1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CIB1 Antibody Picoband®

1 Q&As

Human, Mouse, Rat

$370
Cat # PB9489
100 μg/vial

Anti-CIB1 Monoclonal Antibody

Human

ELISA, IHC, WB

$380
Cat # M01797
100ul

CIB1 (NM_006384) Human Recombinant Protein

$813
Cat # PROTQ99828
20 µg

CIB1 (NM_006384) Human Over-expression Lysate

Human

$628
Cat # LS010519
100 µg

CIB1 Overview

Facts about Calcium and integrin-binding protein 1.

CIB1 3D structure. Source: alphafold

Calcium and integrin-binding protein 1 (CIB1)

Calcium-binding protein which plays a role in the regulation of many cellular processes, such as cell differentiation, cell division, cell proliferation, cell migration, thrombosis, angiogenesis, cardiac hypertrophy and apoptosis. Participates in the endomitotic cell cycle of megakaryocyte, a kind of mitosis in which both karyokinesis and cytokinesis are interrupted.

Plays a role in integrin signaling by negatively regulating alpha-IIb/beta3 activation in thrombin- stimulated megakaryocytes preventing platelet aggregation. Up- regulates PTK2/FAK1 activity, and is also required for the recruitment of PTK2/FAK1 to focal adhesions; it thus seems to play an important role in focal adhesion formation.

Gene Information

Human
Gene Name:	CIB1
Uniprot:	Q99828
Entrez:	10519

Family

Belongs to:

No superfamily

Alternative Names

calcium and integrin binding 1 (calmyrin); Calcium- and integrin-binding protein; Calmyrin; CIB1; CIBcalcium and integrin binding protein; CIBP; DNA-dependent protein kinase interacting protein; DNA-PKcs-interacting protein; Kinase-interacting protein; KIP; KIP1; KIPcalcium and integrin binding, protein kinase interacting protein; PRKDCIP; SIP2-28; SIP2-28calcium and integrin-binding protein 1; Snk interacting protein 2-28; SNK-interacting protein 2-28

Molecular Weight

Mass (kDA):
21.703 kDA

Genomic Context


Human

Location:	15q26.1
Sequence:	15; NC_000015.10 (90229975..90265759, complement)

Tissue Specificity

Detected in platelets and in cell lines of megakaryocytic and erythrocytic lineages. Both isoform 1 and isoform 2 are detected in various cancer cell lines, with isoform 2 being the predominant form (at protein level). Ubiquitously expressed.

Subcellular Localizations

Membrane; Lipid-anchor. Cell membrane, sarcolemma. Cell membrane. Apical cell membrane. Cell projection, ruffle membrane. Cell projection, filopodium tip. Cell projection, growth cone. Cell projection, lamellipodium. Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, perinuclear region. Nucleus. Cell projection, neuron projection. Perikaryon. Colocalized with PPP3R1 at the cell membrane of cardiomyocytes in the hypertrophic heart (By similarity). Colocalized with NBR1 to the perinuclear region. Colocalizes with TAS1R2 in apical re