TGFBRAP1 Antibodies

AND TGFBRAP1 ELISA kits, TGFBRAP1 Proteins

Many biological assays use antibodies to detect TGFBRAP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TGFBRAP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TGFBRAP1 antibodies...

We validate the specificity of these antibodies to TGFBRAP1 by testing them on tissues known to express TGFBRAP1 positively and negatively. Browse below to find the TGFBRAP1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TGFBRAP1 Infographic by Boster Bio

All TGFBRAP1 Products

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Product

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Specificity

Applications

Price

Anti-TGFA1 TGFBRAP1 Antibody

Human

ELISA, WB

$380
Cat # A08493
100ul

Human TGFBRAP1 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTQ8WUH2
Starting from 10ug

TGFBRAP1 Overview

Facts about Transforming growth factor-beta receptor-associated protein 1.

TGFBRAP1 3D structure. Source: alphafold

Transforming growth factor-beta receptor-associated protein 1 (TGFBRAP1)

Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling.

May recruit SMAD4 into the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2. .

Gene Information

Human
Gene Name:	TGFBRAP1
Uniprot:	Q8WUH2
Entrez:	9392

Family

Belongs to:

TRAP1 family

Alternative Names

TGF-beta receptor-associated protein 1; transforming growth factor, beta receptor associated protein 1; transforming growth factor-beta receptor-associated protein 1; TRAP1; TRAP-1

Molecular Weight

Mass (kDA):
97.158 kDA

Genomic Context


Human

Location:	2q12.1-q12.2
Sequence:	2; NC_000002.12 (105249408..105329735, complement)

Subcellular Localizations

Cytoplasm. Early endosome. Colocalizes with TGF-beta receptors in the absence of signaling.

Diseases

Malignant Neoplasms
Acquired Immunodeficiency Syndrome
Lung Injury
Hepatitis, Chronic
Respiratory Distress Syndrome, Adult
Hepatitis C, Chronic
Pre-eclampsia
Malignant Neoplasm Of Lung
Pseudomonas Infections
Degenerative Polyarthritis
Respiratory Distress

Immunologic Deficiency Syndromes
Neoplasms
Colitis
Acute Lung Injury
Dysequilibrium Syndrome
Malignant Neoplasm Of Prostate

Interacting Proteins

VPS11
VPS16
VPS8

Pathways

Gastrulation
Cell Death
Cell Cycle
Fibroblast Proliferation
Pathogenesis

PTMs

Phosphorylation

Research Areas

Angiogenesis
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TGFBRAP1

References

PMID: 9545258 by Charng M.-J., et al. A novel protein distinguishes between quiescent and activated forms of the type I transforming growth factor beta receptor.

PMID: 10051563 by Provost P., et al. Interaction of 5-lipoxygenase with cellular proteins.