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- Table of Contents
Facts about Carbohydrate sulfotransferase 3.
Can also sulfate Gal residues of keratan sulfate, another glycosaminoglycan, and the Gal residues in sialyl N- acetyllactosamine (sialyl LacNAc) oligosaccharides. May play a role in the maintenance of innocent T-lymphocytes in the spleen.
Human | |
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Gene Name: | CHST3 |
Uniprot: | Q7LGC8 |
Entrez: | 9469 |
Belongs to: |
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sulfotransferase 1 family |
C6ST1; C6ST-1; C6ST1HSD; C6STEC 2.8.2.17; carbohydrate (chondroitin 6) sulfotransferase 3; Carbohydrate Sulfotransferase 3; Chondroitin 6-O-sulfotransferase 1; Chondroitin 6-sulfotransferase; CHST3; EC 2.8.2; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0; GST-0
Mass (kDA):
54.706 kDA
Human | |
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Location: | 10q22.1 |
Sequence: | 10; NC_000010.11 (71964395..72013562) |
Widely expressed in adult tissues. Expressed in heart, placenta, skeletal muscle and pancreas. Also expressed in various immune tissues such as spleen, lymph node, thymus and appendix.
Golgi apparatus membrane; Single-pass type II membrane protein.
PMID: 9714738 by Fukuta M., et al. Molecular cloning and expression of human chondroitin 6- sulfotransferase.
PMID: 9883891 by Tsutsumi K., et al. Functional expression and genomic structure of human chondroitin 6- sulfotransferase.