CHRNA6 Antibodies

AND CHRNA6 ELISA kits, CHRNA6 Proteins

Many biological assays use antibodies to detect CHRNA6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHRNA6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHRNA6 antibodies...

We validate the specificity of these antibodies to CHRNA6 by testing them on tissues known to express CHRNA6 positively and negatively. Browse below to find the CHRNA6 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CCN4 Next: P4HA2

CHRNA6 Infographic by Boster Bio

All CHRNA6 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CHRNA6 Antibody

Human, Mouse

$405
Cat # A06421
100ul

Anti-ACHA6 CHRNA6 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A06421-1
100ul

Human CHRNA6 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTQ15825
Starting from 20ug

CHRNA6 Overview

Facts about Neuronal acetylcholine receptor subunit alpha-6.

CHRNA6 3D structure. Source: alphafold

Neuronal acetylcholine receptor subunit alpha-6 (CHRNA6)

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. .

Gene Information

Human
Gene Name:	CHRNA6
Uniprot:	Q15825
Entrez:	8973

Family

Belongs to:

ligand-gated ion channel (TC 1.A.9) family

Alternative Names

CHNRA6; cholinergic receptor, nicotinic, alpha 6; cholinergic receptor, nicotinic, alpha polypeptide 6; CHRNA6; neuronal acetylcholine receptor subunit alpha-6; Nicotinic Acetylcholine R alpha 6; Nicotinic Acetylcholine Ra6

Molecular Weight

Mass (kDA):
56.898 kDA

Genomic Context


Human

Location:	8p11.21
Sequence:	8; NC_000008.11 (42752620..42768786, complement)

Subcellular Localizations

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Diseases

Nicotine Dependence
Tobacco Use Disorder
Parkinson Disease
Epilepsy, Frontal Lobe
Malignant Neoplasms
Epilepsy
Neurodegenerative Disorders
Malignant Neoplasm Of Lung
Bipolar Disorder
Lung Neoplasms
Schizophrenia
Alzheimer's Disease

Tobacco Dependence Syndrome
Idiopathic Generalized Epilepsy
Dizziness
Ataxia
Epilepsy, Generalized
Partial Seizure
Sleep Disorders

Pathways

Response To Nicotine
Chromosome Localization
Localization
Righting Reflex
Synaptic Transmission
Cellular Response To Nicotine
Neuron Development
Reflex
Regulation Of Nervous System Development
Reverse Transcription

System Development
Nervous System Development
Social Behavior
Pathogenesis

PTMs

Disulfide bond

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHRNA6

References

PMID: 8906617 by Elliott K.J., et al. Comparative structure of human neuronal alpha 2-alpha 7 and beta 2- beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.

PMID: 27344019 by Arvaniti M., et al. Functional interaction between Lypd6 and nicotinic acetylcholine receptors.