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Chondrolectin Antibodies
AND CHODL ELISA kits, Chondrolectin Proteins
Many biological assays use antibodies to detect Chondrolectin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Chondrolectin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Chondrolectin antibodies...
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CHODL Overview
Facts about Chondrolectin.
Chondrolectin (CHODL)
May play a role in the development of the nervous system such as in neurite outgrowth and elongation. May be involved in motor axon growth and guidance.
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Gene Information
| Human | |
|---|---|
| Gene Name: | CHODL |
| Uniprot: | Q9H9P2 |
| Entrez: | 140578 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
C21orf68; CHODL; Chondrolectin; chromosome 21 open reading frame 68; FLJ12627; MT75; PRED12; Transmembrane protein MT75
Molecular Weight
Mass (kDA):
30.431 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 21q21.1 |
| Sequence: | 21; NC_000021.9 (17819329..18267371) |
Tissue Specificity
Found in spleen, testis, prostate and fetal liver. Expression limited to vascular muscle of testis, smooth muscle of prostate stroma, heart muscle, skeletal muscle, crypts of small intestine, and red pulp of spleen. B lymphocytes express isoform 2 only; peripheral blood T lymphocytes express isoform 3 only; granulocytes and monocytes express neither isoform 2 nor isoform 3. During development of T lymphocytes, bone marrow progenitor cells express isoform 2 only; thymocytes at different stages of maturation express predominantly isoform 2 and weakly isoform 3, and mature thymocytes express only isoform 2.
Subcellular Localizations
Cytoplasm. Membrane; Single-pass type I membrane protein.; [Isoform 2]: Endoplasmic reticulum. Endoplasmic reticulum membrane; Single-pass type I membrane protein.; [Isoform 3]: Cytoplasm.
Diseases
- Muscular Atrophy
- Atrophy
- Nervousness
- Spinal Muscular Atrophy
- Avulsed Wound
- Sclerosis
- Primary Lateral Sclerosis
- Lung Neoplasms
- Non-small Cell Lung Carcinoma
- Spinal Cord Injuries
- Trauma, Nervous System
Pathways
- Localization
- Regeneration
- Cell Development
- Axon Regeneration
- Cell Growth
- Innervation
PTMs
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHODL
bosterbio.com/bosterbio-gene-info-cards/CHODL
References
PMID: 12079284 by Weng L., et al. Molecular cloning and characterization of human chondrolectin, a novel type I transmembrane protein homologous to C-type lectins.
PMID: 12621022 by Weng L., et al. A novel alternative spliced chondrolectin isoform lacking the transmembrane domain is expressed during T cell maturation.