N-chimaerin Antibodies

AND CHN1 ELISA kits, N-chimaerin Proteins

Many biological assays use antibodies to detect N-chimaerin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with N-chimaerin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop N-chimaerin antibodies...

We validate the specificity of these antibodies to N-chimaerin by testing them on tissues known to express CHN1 positively and negatively. Browse below to find the CHN1 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CDH12 Next: CHN2

CHN1 Infographic by Boster Bio

All CHN1 Products

Product

Figures

Specificity

Applications

Price

Anti-N-chimaerin CHN1 Antibody

Human, Mouse, Rat

$405
Cat # A04240
100ul

CHN 1 (CHN1) (NM_001025201) Human Recombinant Protein

$1249
Cat # PROTP15882
20 µg

Anti-CHN 1 (CHN1) Mouse Monoclonal Antibody [Clone ID: OTI1C9]

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$523
Cat # M04240
100 µl

Anti-CHN 1 (CHN1) Mouse Monoclonal Antibody [Clone ID: OTI3C6]

Dog, Human, Monkey, Mouse, Rat

IHC, WB

$523
Cat # M04240-2
100 µl

Anti-CHN 1 (CHN1) Mouse Monoclonal Antibody [Clone ID: OTI2G6]

+18

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M04240-1
100 µl

CHN 1 (CHN1) (NM_001822) Human Over-expression Lysate

Human

$628
Cat # LS001123
100 µg

CHN1 Overview

Facts about N-chimaerin.

CHN1 3D structure. Source: alphafold

N-chimaerin (CHN1)

GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance.

Gene Information

Human
Gene Name:	CHN1
Uniprot:	P15882
Entrez:	1123

Family

Belongs to:

No superfamily

Alternative Names

a2-chimaerin; A-chimaerin; alpha-chimerin; ARHGAP2RhoGAP2; chimerin (chimaerin) 1; CHNDuane retraction syndrome 2; DURS2; NC; N-chimaerin; n-chimerin; Rho GTPase-activating protein 2; RHOGAP2

Molecular Weight

Mass (kDA):
53.172 kDA

Genomic Context


Human

Location:	2q31.1
Sequence:	2; NC_000002.12 (174798809..175005381, complement)

Tissue Specificity

In neurons in brain regions that are involved in learning and memory processes.

Diseases

Duane Retraction Syndrome
Hepatitis
Strabismus
Esotropia
Blepharoptosis
Ocular Motility Disorders
Nephropathy Toxic
Prion Diseases
Acquired Immunodeficiency Syndrome
Malignant Neoplasm Of Breast
Mirror Movements Disorder
Malignant Neoplasms
Chondrosarcoma

Neoplasms
Double Elevator Palsy
Nephrotic Syndrome
Hepatitis C
Diabetes Mellitus
Nerve Paralysis
Cranial Nerve Diseases

Interacting Proteins

HEMK1
NCK2

Pathways

Innervation
Transport
Cell Adhesion
Reverse Transcription
Dna Amplification
Locomotion
Neurogenesis

Epiboly
Excretion

PTMs

Deacetylation

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHN1

References

PMID: 2299665 by Hall C., et al. Novel human brain cDNA encoding a 34,000 Mr protein n-chimaerin, related to both the regulatory domain of protein kinase C and BCR, the product of the breakpoint cluster region gene.

PMID: 1445199 by Lim H.H., et al. Developmental regulation and neuronal expression of the mRNA of rat n-chimaerin, a p21rac GAP:cDNA sequence.