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- Table of Contents
Facts about Calcium homeostasis endoplasmic reticulum protein.
Human | |
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Gene Name: | CHERP |
Uniprot: | Q8IWX8 |
Entrez: | 10523 |
Belongs to: |
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No superfamily |
calcium homeostasis endoplasmic reticulum protein; DAN16; DAN26; ERPROT 213-21; ERPROT213-21; protein with polyglutamine repeat; SCAF6; SRA1; SR-related CTD associated factor 6; SR-related CTD-associated factor 6
Mass (kDA):
103.702 kDA
Human | |
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Location: | 19p13.11 |
Sequence: | 19; NC_000019.10 (16517894..16542437, complement) |
Expressed in brain, placenta, lung, liver, kidney, pancreas, cardiac and skeletal muscle, and in cultured HEL and Dami cells.
Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum. Distributed throughout the cytoplasm and also localizes to the perinuclear region of both human erythroleukemia (HEL) cells and Jurkat cells. Colocalizes with ITPR1.
PMID: 8896557 by Imbert G., et al. Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats.
PMID: 10794731 by LaPlante J.M., et al. Cloning of human Ca2+ homoeostasis endoplasmic reticulum protein (CHERP): regulated expression of antisense cDNA depletes CHERP, inhibits intracellular Ca2+ mobilization and decreases cell proliferation.