CHD1 Antibodies

Chromodomain-helicase-DNA-binding protein 1 (CHD1)

ATP-dependent chromatin-remodeling factor which serves as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step.

Regulates negatively DNA replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a particular chromatin configuration across the genome.

Gene Information

Human
Gene Name:	CHD1
Uniprot:	O14646
Entrez:	1105

Family

Belongs to:
SNF2/RAD54 helicase family

Alternative Names

ATP-dependent helicase CHD1; CHD1; CHD-1; chromodomain helicase DNA binding protein 1; chromodomain-helicase-DNA-binding protein 1; DKFZp686E2337; EC 3.6.1; EC 3.6.4.12

Molecular Weight

Mass (kDA):
196.688 kDA

Genomic Context

Human
Location:	5q15-q21.1
Sequence:	5; NC_000005.10 (98853985..98929772, complement)

Tissue Specificity

Expressed in many tissues including in the brain, where the highest level of expression is found in the cerebellum and basal ganglia.

Subcellular Localizations

Nucleus. Cytoplasm. Is released into the cytoplasm when cells enter mitosis and is reincorporated into chromatin during telophase-cytokinesis.

Diseases

• Malignant Neoplasms
• Neoplasms
• Stomach Neoplasms
• Prostatic Neoplasms
• Malignant Neoplasm Of Prostate
• Malignant Neoplasm Of Stomach
• Malignant Neoplasm Of Breast
• Carcinoma
• Mammary Neoplasms
• Cell Transformation, Neoplastic
• Hiv Infections
• Leukemia

• Neoplasm Metastasis
• Charge Syndrome
• Coronary Heart Disease
• Non-neoplastic Disorder
• Neuronal Migration Disorders
• Ehlers-danlos Syndrome

Pathways

• Chromatin Remodeling
• Methylation
• Atp-dependent Chromatin Remodeling
• Chromatin Assembly
• Histone Modification
• Localization
• Chromatin Organization
• Dna Methylation
• Histone Acetylation
• Histone Methylation
• Rna Interference
• Nucleosome Positioning
• Dna Replication

• Nucleosome Assembly
• Sex Determination
• Interphase
• Nucleosome Organization
• Histone Exchange
• Gene Silencing
• Cell Growth

PTMs

• Methylation
• Phosphorylation
• Acetylation
• Deacetylation

• Demethylation
• Reduction
• Cleavage
• Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHD1

Boster Bio - Best Uses Of The CHD1 Marker

Boster Bio is a new website that you will be exploring. You might be curious as to what this antibody is and how it can best be used. Steven Boster Bio's founder and CEO, developed his first product back in 1993. He is commonly known as "he, who converts science to the lavatory". He has since developed dozens of different products for IHC and thousands of primary antibodies. By the late 90s, he was the largest antibody catalog company in China. Boster Bio developed its own proprietary ELISA platform PicoKine in response to trade secrets. It delivers high-sensitivity ELISA kit kits.

Boster Bio: Anti-KHDRBS2 Antibody

This antibody is a monoclonal anti-KHDRBS2 antibody. It is used to detect Khdrbs2 present in samples. This antibody reacts both with animal and human samples. Boster Bio has developed anti-KHDRBS2 antibodies using rabbits as models. This protein acts as a key regulator of alternative transcript splicing and influences mRNA expression by binding to a purine rich exonic enhancer.

Anti-Bax (S4) Antibody

The CHD1 marker is a protein that contains a region called spliceosome. It is expressed in chromosomes. Its greatest uses are currently unknown. There are a number of ways to detect this protein in biological samples. This article will discuss some of these uses.

History of Steven Boster

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Steve Boster was born in Joliet, IL, on April 2, 1922. He was the child of James Boster, Evelyn Meier, a sales manager for many decades. He also served in U.S. Army. He was a member Concordia Hall, Staunton, VA. Steve is survived his 2 daughters, Natosha Peck & Crystal Boster, his wife Natosha Peck as well as his two sons Jonathan & Cory and his sister Tammy. His nieces & nephews also survived him.