CEP85 Antibodies

AND CEP85 ELISA kits, CEP85 Proteins

Many biological assays use antibodies to detect CEP85, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CEP85 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CEP85 antibodies...

We validate the specificity of these antibodies to CEP85 by testing them on tissues known to express CEP85 positively and negatively. Browse below to find the CEP85 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CEP85 Infographic by Boster Bio

All CEP85 Products

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Specificity

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Price

Anti-Centrosomal protein of 85 kDa CEP85 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A12164
100ul

CCDC21 (CEP85) (NM_022778) Human Over-expression Lysate

Human

$628
Cat # LS064793
100 µg

CEP85 Overview

Facts about Centrosomal protein of 85 kDa.

CEP85 3D structure. Source: alphafold

Centrosomal protein of 85 kDa (CEP85)

Acts as a negative regulator of NEK2 to maintain the centrosome integrity in interphase. Suppresses centrosome disjunction by inhibiting NEK2 kinase activity (PubMed:26220856).

Gene Information

Human
Gene Name:	CEP85
Uniprot:	Q6P2H3
Entrez:	64793

Family

Belongs to:

CEP85 family

Alternative Names

coiled-coil domain containing 21; coiled-coil domain-containing protein 21; DKFZP434L0117; DKFZp434P232; FLJ13976; FLJ22000

Molecular Weight

Mass (kDA):
85.639 kDA

Genomic Context


Human

Location:	1p36.11
Sequence:	1; NC_000001.11 (26234179..26278808)

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Nucleus, nucleolus. Localizes to centrosomes and nucleolus in interphase. Upon entry into mitosis, relocates from nucleolus and accumulates at spindle poles (PubMed:21399614). Associated with the pericentriolar material. Localizes to centrosomes at a low level in G1 phase and a slightly increased level in S phase, with gradually elevated levels during G2 phase. The levels at centrosomes further increase at G2/M, reaching a peak at spindle poles at early mitotic stages and remain high unti

Interacting Proteins

TERF1

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CEP85

References

PMID: 21399614 by Jakobsen L., et al. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

PMID: 26220856 by Chen C., et al. Characterization of Cep85 - a new antagonist of Nek2A that is involved in the regulation of centrosome disjunction.