CEP120 Antibodies

AND CEP120 ELISA kits, CEP120 Proteins

Many biological assays use antibodies to detect CEP120, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CEP120 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CEP120 antibodies...

We validate the specificity of these antibodies to CEP120 by testing them on tissues known to express CEP120 positively and negatively. Browse below to find the CEP120 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CEP120 Infographic by Boster Bio

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CEP120 (NM_153223) Human Over-expression Lysate

Human

$960
Cat # LS153241
100 µg

CEP120 Overview

Facts about Centrosomal protein of 120 kDa.

CEP120 3D structure. Source: alphafold

Centrosomal protein of 120 kDa (CEP120)

Plays a role in the microtubule-dependent coupling of the nucleus along with the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development.

Also implicated in the migration and selfrenewal of neural progenitors. Required for centriole duplication and maturation during mitosis and following ciliogenesis (By similarity).

Gene Information

Human
Gene Name:	CEP120
Uniprot:	Q8N960
Entrez:	153241

Family

Belongs to:

CEP120 family

Alternative Names

CCDC100; centrosomal protein 120kDa; centrosomal protein of 120 kDa; coiled-coil domain containing 100; coiled-coil domain-containing protein 100; DKFZp686I06246; FLJ36090

Molecular Weight

Mass (kDA):
112.64 kDA

Genomic Context


Human

Location:	5q23.2
Sequence:	5; NC_000005.10 (123344885..123423842, complement)

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo.

Diseases

Systemic Infection
Staphylococcal Infections
Staphylococcus Aureus Infection

Interacting Proteins

ANK2
CEP162

Pathways

Nuclear Migration
Interkinetic Nuclear Migration
Neurogenesis
Localization

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CEP120

References

PMID: 25361962 by Shaheen R., et al. A founder CEP120 mutation in Jeune asphyxiating thoracic dystrophy expands the role of centriolar proteins in skeletal ciliopathies.

PMID: 27185865 by Chang C.W., et al. CEP295 interacts with microtubules and is required for centriole elongation.