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- Table of Contents
Facts about Centromere protein Q.
Plays an essential role in chromosome congression and in the recruitment of CENP-O complex (which includes CENPO, CENPP, CENPQ and CENPU), CENPE and PLK1 to the kinetochores (PubMed:25395579). .
Human | |
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Gene Name: | CENPQ |
Uniprot: | Q7L2Z9 |
Entrez: | 55166 |
Belongs to: |
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CENP-Q/OKP1 family |
C6orf139; CENP-QFLJ10545; centromere protein Q; chromosome 6 open reading frame 139
Mass (kDA):
30.595 kDA
Human | |
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Location: | 6p12.3 |
Sequence: | 6; NC_000006.12 (49463327..49493107) |
Nucleus. Chromosome, centromere. Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
PMID: 16622420 by Okada M., et al. The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.
PMID: 16622419 by Foltz D.R., et al. The human CENP-A centromeric nucleosome-associated complex.