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- Table of Contents
Facts about Carcinoembryonic antigen-related cell adhesion molecule 7.
Human | |
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Gene Name: | CEACAM7 |
Uniprot: | Q14002 |
Entrez: | 1087 |
Belongs to: |
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immunoglobulin superfamily |
Carcinoembryonic antigen CGM 2; Carcinoembryonic antigen CGM2; Carcinoembryonic antigen gene family member 2; Carcinoembryonic antigen related cell adhesion molecule 7; CEA; CEACAM 7; CEACAM7; CEACAM-7; CGM 2; CGM2
Mass (kDA):
29.379 kDA
Human | |
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Location: | 19q13.2 |
Sequence: | 19; NC_000019.10 (41673303..41688270, complement) |
Expressed in columnar epithelial cells of the colon (at protein level) (PubMed:10436421). Strongly down- regulated in colonic adenocarcinomas.
Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane. Localized to the apical glycocalyx surface.
PMID: 7806520 by Thompson J., et al. CGM2, a member of the carcinoembryonic antigen gene family is down- regulated in colorectal carcinomas.
PMID: 9135022 by Thompson J., et al. Down-regulation of carcinoembryonic antigen family member 2 expression is an early event in colorectal tumorigenesis.