CEACAM3 Antibodies

AND CEACAM3 ELISA kits, CEACAM3 Proteins

Many biological assays use antibodies to detect CEACAM3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CEACAM3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CEACAM3 antibodies...

We validate the specificity of these antibodies to CEACAM3 by testing them on tissues known to express CEACAM3 positively and negatively. Browse below to find the CEACAM3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CEACAM3 Infographic by Boster Bio

All CEACAM3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CEACAM3 Antibody

Human, Mouse

$405
Cat # A06613
100ul

CEACAM3 (NM_001815) Human Recombinant Protein

$1062
Cat # PROTP40198
20 µg

Human CEACAM3 ELISA Kit PicoKine®

Human

ELISA

$750
Cat # EK2163
96 wells/kit, with removable strips.

CEACAM3 (NM_001815) Human Over-expression Lysate

Human

$628
Cat # LS001084
100 µg

CEACAM3 Overview

Facts about Carcinoembryonic antigen-related cell adhesion molecule 3.

CEACAM3 3D structure. Source: alphafold

Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3)

Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding germs, such as Neissiria, Moxarella and Haemophilus species, thus playing an essential role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.

Gene Information

Human
Gene Name:	CEACAM3
Uniprot:	P40198
Entrez:	1084

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

CD66d; CEA; CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3; CEACAM-3; CGM1; W264; W282

Molecular Weight

Mass (kDA):
27.091 kDA

Genomic Context


Human

Location:	19q13.2
Sequence:	19; NC_000019.10 (41796587..41811554)

Tissue Specificity

CGM1a, the predominant CGM1 transcript, is granulocyte-specific. Not detected out of the granulocytic lineage, such as monocytes, lymphocytes, spleen, testis, colon, brain, liver, pancreas, thymus, ovary, placenta, skeletal muscle, prostate, small intestine, heart, lung and kidney.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Tissue Adhesions
Gonorrhea
Neoplasms
Cell Invasion
Infective Disorder
Leukemia
Malignant Neoplasms
Bacterial Infections
Influenza
Melanoma
Fibrosis
Pneumonia
Burkitt Lymphoma

Malignant Tumor Of Colon
Lung Diseases
Myeloid Leukemia, Chronic
Carcinoma
Lung Diseases, Interstitial
Viral Upper Respiratory Tract Infection
Usual Interstitial Pneumonitis

Pathways

Cell Adhesion
Phagocytosis
Neutrophil Activation
Cell-cell Adhesion
Cell Proliferation
Endocytosis
Virulence
Localization
Cell-cell Recognition
Cell Killing
Receptor Clustering
Immune Response
Tropism

Senescence
Gene Conversion
Cell Death
Cell Differentiation
Regulation Of Cell Proliferation
Angiogenesis
Pathogenesis

PTMs

Phosphorylation
Cleavage

Gpi Anchoring
Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CEACAM3

References

PMID: 2050678 by Kuroki M., et al. Molecular cloning of nonspecific cross-reacting antigens in human granulocytes.

PMID: 8508798 by Nagel G., et al. Genomic organization, splice variants and expression of CGM1, a CD66- related member of the carcinoembryonic antigen gene family.