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- Table of Contents
Facts about Cerebellar degeneration-related antigen 1.
Human | |
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Gene Name: | CDR1 |
Uniprot: | P51861 |
Entrez: | 1038 |
Belongs to: |
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No superfamily |
Cerebellar degeneration-related antigen 1
Mass (kDA):
31.279 kDA
Human | |
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Location: | Xq27.1 |
Sequence: | X; NC_000023.11 (140783260..140784558, complement) |
Brain; predominantly expressed in normal neuroectodermal tissues and in certain malignant tumors.
This article will explain everything you need to know about Boster Bio’s Anti–CDR1 Marker. You'll learn all about this marker's history and uses in biology, as well as its clone lineage. This article also contains information about Steven Boster, his work, and more. This product is useful for scientists from all walks of science, regardless of their experience. This product is not recommended to be used in all applications.
Boster Bio Anti CDR1Markers are anti-rabies that react with Human, Mouse and Rat proteins. They can be stored at room temperature for one year and are available in lyophilized forms. They can be stored in a solution with 50% glycerol (0.02% sodium azide) and PBS. Boster Bio Anti CDR1 markers are designed to work on both WB as well as IHC.
Complex parameters like the use of V or J sequences or the convergence evolution of CDR3 series determine antigen specificity. Figure 1d illustrates a 12-triplet maximum score of 1-DBC. Figure 1d shows that each feature has a unique starting position relative the length of the CDR3 series. The length of CDR3s can vary between individuals. Therefore, each feature's starting position must be determined using the CDR3 sequence.
Boster Bio's clone lines are the result of a novel breeding strategy that uses genetic recombination. The company has designed a line ELISA Kits for the detection and analysis of biomarkers within the areas of neuroscience, cancer, or development. The sensitivity of these kits reaches the picogram level. tebu-bio distributes Boster Bio immunological reagents.
The variable regions of Ig heavy chain and light chain genes are responsible for B-cell receptor diversity and can be used to estimate the diversification of B-cell repertoires. Clone lineages are useful for the detection and quantification of SHMs. Using clone lineages, Boster Bio's methodology enables rapid identification of clone-specific antibodies and other antigens that may be ineffective.
CLH001 contains more 50 copies of the 12 CLH001 sequences. Each copy has its clonotype number. CDR1 can be used to identify lines with high levels or diversity. The TC-mAb mouse model was used to genotype the most common clone lines. The results showed that clone lines were more representative of genetic diversity of Boster Bio clone ClH001 than the VK models.
Steven Boster's story begins in 1993, when he created his first product. After creating hundreds and selling them to research laboratories, Boster earned his nickname "the man that converts science in a lavatory". His company quickly became China’s biggest catalog antibody company. PicoKine(tm), his proprietary ELISA platform that he developed, was later patent. This proprietary platform allows him deliver high-sensitivity ELISA Kits that allow scientists to quickly and efficiently detect different molecules.
Steve Boster is an Army veteran with a fascinating past. He was the child of James and Evelyn Meier. He spent many years in sales. He was also a member of Concordia Hall, Staunton, and served in the U.S. Army. His children include Crystal Boster (his wife), Natosha Poeck (his daughters), Jack Boster (his brothers), 6 grandchildren, and many nieces or nephews.
PMID: 2326268 by Chen Y.-T., et al. Cerebellar degeneration-related antigen: a highly conserved neuroectodermal marker mapped to chromosomes X in human and mouse.
PMID: 3474619 by Dropcho E.J., et al. Cloning of a brain protein identified by autoantibodies from a patient with paraneoplastic cerebellar degeneration.