CDK5RAP2 Antibodies

AND CDK5RAP2 ELISA kits, CDK5RAP2 Proteins

Many biological assays use antibodies to detect CDK5RAP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDK5RAP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDK5RAP2 antibodies...

We validate the specificity of these antibodies to CDK5RAP2 by testing them on tissues known to express CDK5RAP2 positively and negatively. Browse below to find the CDK5RAP2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CDK5RAP2 Infographic by Boster Bio

All CDK5RAP2 Products

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Specificity

Applications

Price

Anti-CDK5RAP2 Antibody

5 Q&As

Human, Mouse, Rat

ELISA, IHC-P, IF (paraffin)

$335
Cat # A03102
100ul

Anti-CDK5RAP2 Antibody Picoband®

Human

ELISA, IF, ICC, WB

$370
Cat # A03102-2
100 μg/vial

CDK5RAP2 Overview

Facts about CDK5 regulatory subunit-associated protein 2.

CDK5RAP2 3D structure. Source: alphafold

CDK5 regulatory subunit-associated protein 2 (CDK5RAP2)

Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion.

Involved in regulation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter.

Gene Information

Human
Gene Name:	CDK5RAP2
Uniprot:	Q96SN8
Entrez:	55755

Family

Belongs to:

No superfamily

Alternative Names

C48; CDK5 activator-binding protein C48; CDK5 regulatory subunit associated protein 2; CDK5 regulatory subunit-associated protein 2; centrosomal protein 215 kDa; Centrosome-associated protein 215; Cep215; DKFZp686B1070; DKFZp686D1070; FLJ10867; KIAA1633microcephaly, primary autosomal recessive 3; MCPH3

Molecular Weight

Mass (kDA):
215.038 kDA

Genomic Context


Human

Location:	9q33.2
Sequence:	9; NC_000009.12 (120388869..120580170, complement)

Tissue Specificity

Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Golgi apparatus. Cytoplasm. Cytoplasm, cytoskeleton. Found in the pericentriolar region adhering to the surface of the centrosome and in the region of the centrosomal appendages. Localizes to microtubule plus ends in the presence of EB1/MAPRE1. Localization to centrosomes versus Golgi apparatus may be cell type-dependent. For instance, in SK-BR-3 and HEK293F cells, localizes to centrosomes but not to the Golgi apparatus (PubMed:29162697).