CDK5 Antibodies

AND CDK5 ELISA kits, CDK5 Proteins

Many biological assays use antibodies to detect CDK5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDK5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDK5 antibodies...

We validate the specificity of these antibodies to CDK5 by testing them on tissues known to express CDK5 positively and negatively. Browse below to find the CDK5 antibody that suites your experiment. We have 14 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CDK5 Infographic by Boster Bio

All CDK5 Products

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Product

Figures

Specificity

Applications

Price

Anti-Cyclin-dependent-like kinase 5 Cdk5 Antibody Picoband®

1 Citations 1 Q&As

Human, Mouse, Rat

$370
Cat # PA1548
100 μg/vial

Anti-Cyclin-dependent-like kinase 5 Cdk5 Antibody

Human, Mouse, Rat

IHC, WB

$629
Cat # A00511
100uL

Anti-CDK5 Rabbit Monoclonal Antibody

1 Citations 6 Q&As

Human, Mouse, Rat

Flow Cytometry, IP, IHC, WB

$370
Cat # M00511
100 μl

Anti-CDK5 Antibody Picoband®

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A00511-1
100 μg/vial

CDK5 Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$480
Cat # EKC1109
1 kit, containing one 96-well plate and all necessary reagents

CDK5 (Phospho-Tyr15) Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$540
Cat # EKC2315
1 kit, containing two 96-well plates and all necessary reagents

Anti-Cdk5 (phospho-Y15) Antibody

Human, Mouse, Rat

$482
Cat # A00511Y15
100ul

Anti-CDK5 (N-terminus) monoclonal Antibody

Human

ICC, WB

$482
Cat # M00511-1
100ul

Anti-Phospho-Cdk5 (Y15) Antibody

Human, Monkey, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A00511Y15-1
100ul

Anti-Cyclin-dependent-like kinase 5 Cdk5 Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A00511-2
100ul

Human CDK5 Recombinant Protein

SDS-PAGE

$287
Cat # PROTQ00535
Starting from 10ug

Anti-CDK5 Antibody

Human, Mouse

Flow Cytometry, IF, IHC-P, WB

$299
Cat # M00511-2
50 µl

Anti-CDK5 Antibody (C-term)

Human, Mouse

Flow Cytometry, IF, WB

$299
Cat # A00511-3
80 µl

CDK5 (NM_004935) Human Over-expression Lysate

Human

$628
Cat # LS001020
100 µg

CDK5 Overview

Facts about Cyclin-dependent-like kinase 5.

CDK5 3D structure. Source: alphafold

Cyclin-dependent-like kinase 5 (CDK5)

Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by activating abortive cell cycle re-entry. Regulates several neuronal development and physiological processes including neuronal survival, migration and differentiation, axonal and neurite growth, synaptogenesis, oligodendrocyte differentiation, synaptic plasticity and neurotransmission, by phosphorylating key proteins.

Activated by interaction with CDK5R1 (p35) and CDK5R2 (p39), especially in post-mitotic neurons, and boosts CDK5R1 (p35) expression in an autostimulation loop. Phosphorylates many downstream substrates like Rho and Ras family small GTPases (e.

Gene Information

Human
Gene Name:	CDK5
Uniprot:	Q00535
Entrez:	1020

Family

Belongs to:

protein kinase superfamily

Alternative Names

CDK5; CDKN5; Cell division protein kinase 5; cyclin-dependent kinase 5; EC 2.7.11; EC 2.7.11.22; LIS7; protein kinase CDK5 splicing; PSSALRE; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunit

Molecular Weight

Mass (kDA):
33.304 kDA

Genomic Context


Human

Location:	7q36.1
Sequence:	7; NC_000007.14 (151053815..151057897, complement)

Tissue Specificity

Isoform 1 is ubiquitously expressed. Accumulates in cortical neurons (at protein level). Isoform 2 has only been detected in testis, skeletal muscle, colon, bone marrow and ovary.

Subcellular Localizations

[Isoform 1]: Cytoplasm. Cell membrane; Peripheral membrane protein. Perikaryon. Cell projection, lamellipodium. Cell projection, growth cone. Cell junction, synapse, postsynaptic density. In axonal growth cone with extension to the peripheral lamellipodia (By similarity). Under neurotoxic stress and neuronal injury conditions, CDK5R (p35) is cleaved by calpain to generate CDK5R1 (p25) in response to increased intracellular calcium. The elevated level of p25, when in complex with CDK5, leads to its subcellular misallocation as well as its hyperactivation. Colocalizes with CTNND2 in the cell bod