CDK13 Antibodies

AND CDK13 ELISA kits, CDK13 Proteins

Many biological assays use antibodies to detect CDK13, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDK13 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDK13 antibodies...

We validate the specificity of these antibodies to CDK13 by testing them on tissues known to express CDK13 positively and negatively. Browse below to find the CDK13 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CDK13 Infographic by Boster Bio

All CDK13 Products

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Product

Figures

Specificity

Applications

Price

Anti-Cyclin-dependent kinase 13 CDK13 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A05292
100ul

Anti-CDK13 Antibody Picoband®

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A05292-1
100 μg/vial

CDC2L5 (CDK13) (NM_031267) Human Over-expression Lysate

Human

$960
Cat # LS008621
100 µg

CDK13 Overview

Facts about Cyclin-dependent kinase 13.

CDK13 3D structure. Source: alphafold

Cyclin-dependent kinase 13 (CDK13)

Cyclin-dependent kinase which shows CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a crucial regulator of transcription elongation.

Required for RNA splicing, likely by phosphorylating SRSF1/SF2. Required during hematopoiesis.

Gene Information

Human
Gene Name:	CDK13
Uniprot:	Q14004
Entrez:	8621

Family

Belongs to:

protein kinase superfamily

Alternative Names

CDC2L5; CDC2LEC 2.7.11.22; CDC2-related protein kinase 5; Cell division cycle 2-like protein kinase 5; Cell division protein kinase 13; CHEDcell division cycle 2-like 5 (cholinesterase-related cell division controller); Cholinesterase-related cell division controller; cyclin-dependent kinase 13; EC 2.7.11; EC 2.7.11.23; hCDK13; KIAA1791FLJ35215

Molecular Weight

Mass (kDA):
164.923 kDA

Genomic Context


Human

Location:	7p14.1
Sequence:	7; NC_000007.14 (39949664..40099580)

Tissue Specificity

Expressed in fetal brain, liver, muscle and in adult brain. Also expressed in neuroblastoma and glioblastoma tumors.

Subcellular Localizations

Nucleus speckle.

Diseases

Malignant Neoplasms
Hiv Infections
Cell Invasion
Cell Transformation, Neoplastic
Liver Carcinoma
Ataxia
Genomic Instability
Carcinoma
Immunologic Deficiency Syndromes
Ataxia Telangiectasia
Neoplasms
Hemophilia A

Telangiectasis
Severe Hereditary Factor Viii Deficiency Disease
Malignant Neoplasm Of Ovary
Chimera Disorder
Colorectal Cancer
Hyperplasia

Interacting Proteins

C1QBP
CCNK

Pathways

Localization
Chemotaxis
Cell Cycle
Protein Phosphorylation
Transport
Peptide Transport
Colony Morphology
Mitosis
Dna Repair
Regulation Of Gene Expression
Megakaryocyte Development
Demethylation
Embryo Development

Methylation
Cell Division
Dna Replication
Mrna Splicing
Translation
Cell Differentiation
Mitotic Cell Cycle

PTMs

Phosphorylation
Reduction
Deamination

Acetylation
Methylation
Deamidation

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDK13

References

PMID: 11162436 by Marques F., et al. A new subfamily of high molecular mass CDC2-related kinases with PITAI/VRE.

PMID: 1731328 by Lapidot-Lifson Y., et al. Cloning and antisense oligodeoxynucleotide inhibition of a human homolog of cdc2 required in hematopoiesis.