This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Cell division cycle 5-like protein.
Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
Human | |
---|---|
Gene Name: | CDC5L |
Uniprot: | Q99459 |
Entrez: | 988 |
Belongs to: |
---|
CEF1 family |
CDC5 (cell division cycle 5, S. pombe, homolog)-like; CDC5 cell division cycle 5-like (S. pombe); CDC5; Cdc5-like protein; Cdc5-related protein; CEF1; cell division cycle 5-like protein; dJ319D22.1 (CDC5-like protein); dJ319D22.1; hCDC5; KIAA0432; PCDC5RPCDC5-LIKE; Pombe cdc5-related protein
Mass (kDA):
92.251 kDA
Human | |
---|---|
Location: | 6p21.1 |
Sequence: | 6; NC_000006.12 (44387706..44450425) |
Ubiquitously expressed in both fetal and adult tissues.
Nucleus. Nucleus speckle. Cytoplasm. May shuttle between cytoplasm and nucleus.
PMID: 9038199 by Bernstein H.S., et al. Pombe Cdc5-related protein. A putative human transcription factor implicated in mitogen-activated signaling.
PMID: 9598309 by Groenen P.M.A., et al. Rearrangement of the human CDC5L gene by a t(6;19)(p21;q13.1) in a patient with multicystic renal dysplasia.