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CD97 antigen Antibodies
AND CD97 ELISA kits, CD97 antigen Proteins
Many biological assays use antibodies to detect CD97 antigen, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD97 antigen in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD97 antigen antibodies...
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CD97 Infographic by Boster Bio
All CD97 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02982
100 μl
Cat # M02982
100 μl
Human, Rat
Flow Cytometry, IHC, WB
$370
Cat # M02982-1
100 μl/vial
Cat # M02982-1
100 μl/vial
CD97 Overview
Facts about CD97 antigen.
CD97 antigen (CD97)
Receptor possibly involved in both adhesion and signaling procedures early after leukocyte activation. Plays an essential role in leukocyte migration (By similarity).
. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CD97 |
| Uniprot: | P48960 |
| Entrez: | |
Family
| Belongs to: |
|---|
| G-protein coupled receptor 2 family |
Alternative Names
CD97
Molecular Weight
Mass (kDA):
91.869 kDA
Genomic Context
| Human | |
|---|---|
| Location: | |
| Sequence: | ; |
Tissue Specificity
Broadly expressed, found on most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Expressed also abundantly by smooth muscle cells. Expressed in thyroid, colorectal, gastric, esophageal and pancreatic carcinomas too. Expression are increased under inflammatory conditions in the CNS of multiple sclerosis and in synovial tissue of patients with rheumatoid arthritis. Increased expression of CD97 in the synovium is accompanied by detectable levels of soluble CD97 in the synovial fluid.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein.; [CD97 antigen subunit alpha]: Secreted, extracellular space.
Diseases
- Tissue Adhesions
- Neoplasms
- Carcinoma
- Malignant Neoplasms
- Inflammation
- Cell Invasion
- Anaplasia
- Neoplasm Invasiveness
- Malignant Paraganglionic Neoplasm
- Rheumatoid Arthritis
- Arthritis
- Convulsions
Pathways
- Dedifferentiation
- Pathogenesis
- Leukocyte Activation
- Cell Adhesion
- Cell Activation
- Secretion
- Lymphocyte Activation
- Complement Activation
- Inflammatory Response
- Cell Motility
- Cell Cycle
- Cell Differentiation
- Glycosylation
PTMs
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD97
bosterbio.com/bosterbio-gene-info-cards/CD97
References
PMID: 7636245 by Hamann J., et al. Expression cloning and chromosomal mapping of the leukocyte activation antigen CD97, a new seven-span transmembrane molecule of the secretion receptor superfamily with an unusual extracellular domain.
PMID: 8786105 by Hamann J., et al. Structure of the human CD97 gene: exon shuffling has generated a new type of seven-span transmembrane molecule related to the secretin receptor superfamily.