This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about T-cell surface protein tactile.
May function at one time after T and NK cells have penetrated the endothelium with integrins and selectins, when they're actively engaging diseased cells and moving in regions of inflammation. .
Human | |
---|---|
Gene Name: | CD96 |
Uniprot: | P40200 |
Entrez: | 10225 |
Belongs to: |
---|
No superfamily |
CD96 antigenMGC22596; CD96 molecule; CD96; DKFZp667E2122; T cell-activated increased late expression protein; TACTILE; TACTILEincreased late expression; T-cell surface protein tactile
Mass (kDA):
65.634 kDA
Human | |
---|---|
Location: | 3q13.13-q13.2 |
Sequence: | 3; NC_000003.12 (111542118..111665996) |
Expressed on normal T-cell lines and clones, and some transformed T-cells, but no other cultured cell lines tested. It is expressed at very low levels on activated B-cells.
Membrane; Single-pass type I membrane protein.
PMID: 1313846 by Wang P.L., et al. Identification and molecular cloning of tactile. A novel human T cell activation antigen that is a member of the Ig gene superfamily.
PMID: 15034010 by Fuchs A., et al. CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155).