This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
, No Gclids
CD79B Antibodies
AND CD79B ELISA kits, CD79B Proteins
Many biological assays use antibodies to detect CD79B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD79B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD79B antibodies...
Previous: BFSP1
Next: CDK11B
CD79B Infographic by Boster Bio
All CD79B Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # PB9169
100 μg/vial
Cat # PB9169
100 μg/vial
Anti-CD79B Monoclonal Antibody
16 Q&As
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01399
100 μl
Cat # M01399
100 μl
Human
Flow Cytometry, IHC, WB
$523
Cat # M01399-2
100 µl
Cat # M01399-2
100 µl
Human
Flow Cytometry, IF, ICC, WB
$370
Cat # M01399-3
100 μl/vial
Cat # M01399-3
100 μl/vial
CD79B Overview
Facts about B-cell antigen receptor complex-associated protein beta chain.
B-cell antigen receptor complex-associated protein beta chain (CD79B)
Required in collaboration with CD79A for initiation of the signal transduction cascade triggered by the B-cell antigen receptor complex (BCR) which contributes to internalization of the complex, trafficking to late endosomes and antigen presentation. Improves phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CD79B |
| Uniprot: | P40259 |
| Entrez: | 974 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
B29; B29B-cell-specific glycoprotein B29; B-cell antigen receptor complex-associated protein beta chain; CD79B antigen (immunoglobulin-associated beta); CD79b antigen; CD79b molecule, immunoglobulin-associated beta; CD79B; IGB; IGBAGM6; Ig-beta; Immunoglobulin-associated B29 protein
Molecular Weight
Mass (kDA):
26.048 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q23.3 |
| Sequence: | 17; NC_000017.11 (63928740..63932331, complement) |
Tissue Specificity
B-cells.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts.
Diseases
- Leukemia
- Chronic Lymphocytic Leukemia
- Lymphoid Leukemia
- Lymphoma
- B-cell Lymphomas
- Malignant Neoplasms
- Lymphoma, Non-hodgkin
- Neoplasms
- Lymphoproliferative Disorders
- Malignant Paraganglionic Neoplasm
- Leukemia, B-cell
- Diffuse Large B-cell Lymphoma
- Immunologic Deficiency Syndromes
Interacting Proteins
- SGTA
Pathways
- Cell Development
- Cell Activation
- Pathogenesis
- Immune Response
- B Cell Activation
- Transport
- Secretion
- Cell Differentiation
- Cell Proliferation
- B Cell Differentiation
- Localization
- Cell Death
- Cell Maturation
PTMs
- Phosphorylation
- Glycosylation
- Methylation
- Deglycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD79B
bosterbio.com/bosterbio-gene-info-cards/CD79B
References
PMID: 1534761 by Mueller B.S., et al. Cloning and sequencing of the cDNA encoding the human homologue of the murine immunoglobulin-associated protein B29.
PMID: 8486355 by Wood W.J. Jr., et al. Isolation and chromosomal mapping of the human immunoglobulin- associated B29 gene (IGB).