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- Table of Contents
2 Citations 9 Q&As
35 Citations 16 Q&As
37 Citations 16 Q&As
8 Citations 16 Q&As
49 Citations 17 Q&As
3 Citations 11 Q&As
2 Citations 11 Q&As
2 Citations 3 Q&As
4 Citations 16 Q&As
2 Citations
15 Citations
Facts about CD44 antigen.
Adhesion with HA plays an important role in cell migration, tumor growth and development. In cancer cells, may play an significant role in invadopodia formation.
Human | |
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Gene Name: | CD44 |
Uniprot: | P16070 |
Entrez: | 960 |
Belongs to: |
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No superfamily |
CD44 antigen; CD44 molecule (Indian blood group); CD44; CD44R; CDw44; cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; CSPG8; ECMR-III; epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; HCAM; HCELL; hematopoietic cell E- and L-selectin ligand; Heparan sulfate proteoglycan; Hermes antigen; homing function and Indian blood group system; HUTCH-I; Hyaluronate receptor; IN; LHR; MC56; MDU2; MDU2CD44 antigen (homing function and Indian blood group system); MDU3; MDU3CDW44; MIC4; MIC4MGC10468; MUTCH-I; Pgp1; PGP-1; PGP-I; Phagocytic glycoprotein 1
Mass (kDA):
81.538 kDA
Human | |
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Location: | 11p13 |
Sequence: | 11; NC_000011.10 (35139168..35232402) |
Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.
Cell membrane; Single-pass type I membrane protein. Cell projection, microvillus. Colocalizes with actin in membrane protrusions at wounding edges. Co-localizes with RDX, EZR and MSN in microvilli. Localizes to cholesterol-rich membrane-bound lipid raft domains.
PMID: 2466575 by Stamenkovic I., et al. A lymphocyte molecule implicated in lymph node homing is a member of the cartilage link protein family.
PMID: 1840487 by Harn H.-J., et al. The multispecific cell adhesion molecule CD44 is represented in reticulocyte cDNA.
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page