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- Table of Contents
Facts about Leukocyte surface antigen CD53.
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Human | |
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Gene Name: | CD53 |
Uniprot: | P19397 |
Entrez: | 963 |
Belongs to: |
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tetraspanin (TM4SF) family |
antigen MOX44 identified by monoclonal MRC-OX44; CD53 antigentetraspanin-25; CD53 glycoprotein; CD53 molecule; CD53 tetraspan antigen; CD53; cell surface antigen; Cell surface glycoprotein CD53; MOX44; MOX44transmembrane glycoprotein; Tetraspanin-25; TSPAN25; tspan-25; TSPAN25leukocyte surface antigen CD53
Mass (kDA):
24.341 kDA
Human | |
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Location: | 1p13.3 |
Sequence: | 1; NC_000001.11 (110871167..110899936) |
B-cells, monocytes, macrophages, neutrophils, single (CD4 or CD8) positive thymocytes and peripheral T-cells.
Cell membrane. Cell junction. Membrane; Multi-pass membrane protein. Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes.
PMID: 1700763 by Angelisova P., et al. The human leucocyte surface antigen CD53 is a protein structurally similar to the CD37 and MRC OX-44 antigens.
PMID: 2258620 by Amiot M.; Identification and analysis of cDNA clones encoding CD53. A pan- leukocyte antigen related to membrane transport proteins.