CD28 Antibodies

AND CD28 ELISA kits, CD28 Proteins

Many biological assays use antibodies to detect CD28, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD28 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD28 antibodies...

We validate the specificity of these antibodies to CD28 by testing them on tissues known to express CD28 positively and negatively. Browse below to find the CD28 antibody that suites your experiment. We have 9 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: BFSP1 Next: SIGLEC6

CD28 Infographic by Boster Bio

All CD28 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human CD28 ELISA Kit PicoKine®

10 Q&As

Human

ELISA

$499
Cat # EK1429
96 wells/kit, with removable strips.

Anti-CD28 Antibody

Human

ELISA, IF, IHC, WB

$449
Cat # A00065
0.1 mg

Anti-Hu CD28 Purified Monoclonal Antibody

Human, Primate

Flow Cytometry, IP, IHC-F, ICC, WB

$299
Cat # M00065
0.1 mg

Anti-Phospho-CD28 (Y218) Antibody

Human, Mouse

ELISA, WB

$380
Cat # A00065Y218
100ul

Anti- CD28 Monoclonal Antibody

1 Citations

Mouse

IHC-P

$299
Cat # M00065-1
100μg/vial

CD28 (NM_006139) Human Recombinant Protein

$1249
Cat # PROTP10747
20 µg

Anti-CD28 Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A00065-3
100 μg/vial

CD28 (NM_006139) Human Over-expression Lysate

Human

$628
Cat # LS000940
100 µg

Human recombinant CD28 ECD protein, AF

Human

Cell Culture

$77
Cat # PROTP10747-2
5ug,20ug,100ug

CD28 Overview

Facts about T-cell-specific surface glycoprotein CD28.

CD28 3D structure. Source: alphafold

T-cell-specific surface glycoprotein CD28 (CD28)

Involved in T-cell activation, the induction of cell proliferation and cytokine production and marketing of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation (PubMed:8617933).

Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (PubMed:15067037). .

Gene Information

Human
Gene Name:	CD28
Uniprot:	P10747
Entrez:	940

Family

Belongs to:

No superfamily

Alternative Names

CD28 antigen (Tp44); CD28 antigen; CD28 molecule; CD28; MGC138290; T-cell-specific surface glycoprotein CD28; Tp44

Molecular Weight

Mass (kDA):
25.066 kDA

Genomic Context


Human

Location:	2q33.2
Sequence:	2; NC_000002.12 (203706475..203739756)

Tissue Specificity

Expressed in T-cells and plasma cells, but not in less mature B-cells.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell surface.

Diseases

Neoplasms
Autoimmune Reaction
Autoimmune Diseases
Hiv Infections
Malignant Neoplasms
Inflammation
Immunologic Deficiency Syndromes
Tissue Adhesions
Autoimmunity
Decreased Immunologic Activity [pe]
Arthritis
Rheumatoid Arthritis
Infective Disorder

Leukemia
Graft-vs-host Disease
Lymphoma
Virus Diseases
Cytomegalovirus Infections
Carcinoma
Lupus Erythematosus, Systemic

Interacting Proteins

PIK3R1

Pathways

Cell Activation
T Cell Activation
Cell Proliferation
Immune Response
Secretion
Cytokine Production
T Cell Proliferation
Pathogenesis
Cell Death
Cell Cycle
Cell Differentiation
Aging
Cytokine Secretion

Lymphocyte Activation
Senescence
Localization
T Cell Costimulation
Cell Growth
Viral Replication
Cell Division

PTMs

Phosphorylation
Dephosphorylation
Glycosylation
Acetylation
Cleavage
Methylation
Ubiquitination
Demethylation
Reduction
Myristoylation

Phosphorothioation
Nitration
Prenylation
Ribosylation
Biotinylation
Oxidation
Nitrosylation
Gpi Anchoring
Cysteinylation
Farnesylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD28

References

PMID: 2825196 by Aruffo A., et al. Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system.

PMID: 2162892 by Lee K.P., et al. The genomic organization of the CD28 gene. Implications for the regulation of CD28 mRNA expression and heterogeneity.

1 Publications of Boster CD28 Antibodies & ELISA Kits

PubMed ID: 10.1021/acsami.1c08290, Combination of Chidamide-Mediated Epigenetic Modulation with Immunotherapy: Boos...

*More publications can be found for each product on its corresponding product page