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- Table of Contents
2 Citations 5 Q&As
2 Citations 17 Q&As
Facts about B-cell receptor CD22.
Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site could be masked by cis interactions with sialic acids on the same cell surface.
Human | |
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Gene Name: | CD22 |
Uniprot: | P20273 |
Entrez: | 933 |
Belongs to: |
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immunoglobulin superfamily |
B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigenMGC130020; CD22 molecule; CD22; sialic acid binding Ig-like lectin 2; Sialic acid-binding Ig-like lectin 2; Siglec2; Siglec-2; SIGLEC2FLJ22814; T-cell surface antigen Leu-14
Mass (kDA):
95.348 kDA
Human | |
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Location: | 19q13.12 |
Sequence: | 19; NC_000019.10 (35329169..35347361) |
B-lymphocytes.
Cell membrane; Single-pass type I membrane protein.
PMID: 1691828 by Stamenkovic I., et al. The B-cell antigen CD22 mediates monocyte and erythrocyte adhesion.
PMID: 1985119 by Wilson G.L., et al. cDNA cloning of the B cell membrane protein CD22: a mediator of B-B cell interactions.
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