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- Table of Contents
Facts about T-complex protein 1 subunit theta.
As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638). The TRiC complex plays a role in the folding of actin and tubulin (Probable).
Human | |
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Gene Name: | CCT8 |
Uniprot: | P50990 |
Entrez: | 10694 |
Belongs to: |
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TCP-1 chaperonin family |
C21orf112; Cctq; CCT-theta; chaperonin containing TCP1, subunit 8 (theta); chromosome 21 open reading frame 112; D21S246; KIAA0002; PRED71; T-complex protein 1 subunit theta; T-complex protein 1, theta subunit, 10Renal carcinoma antigen NY-REN-15; TCP-1-theta
Mass (kDA):
59.621 kDA
Human | |
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Location: | 21q21.3 |
Sequence: | 21; NC_000021.9 (29056322..29073797, complement) |
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body.
CCT8 is a marker that can be used to help researchers develop high-affinity primaries antibodies. Boster has several products that target this marker, including gene infographics, high-affinity primary antibodies, and even antibody fragments. This article contains more information about Boster’s CCT8 antibodies. This article is not intended for use as a complete guide on the CCT8Marker.
Boster's high-affinity, primary antibody uses the CCT8 marker for recognition of the molecule of concern. It is designed for cell signaling experiments. The company offers many products to support research. The company offers several products for research purposes, including rabbit anti llama antibodies and goat anti llama antibodies. Other products are manufactured by companies like Capricorn Products and Cayman Chemical Company. They offer monoclonal and polyclonal antibody, isotype controls, ELISA kits, and polyclonal antibody.
Another company that produces monoclonal antibodies is the Goodwin Institute for Cancer Research. These antibodies were first developed by the institute. They can now be purchased through Virusys. There are a few other companies involved in antibody research. HyTest is one example of a supplier for immunological reagents, antibodies, that can be used in a variety of applications. Their portfolio also includes markers for autoimmune and veterinary disease, as well as cardiac tissues.
Advanced Targeting Systems is another company that produces neuroendocrine antibodies. This company produces monoclonal antibodies and polyclonal anti-DNA polymerases. This company also manufactures monoclonal antibodies against neurotransmitters, fatty acids, and NO-molecules. They offer monoclonal HIV and Hepatitis A/C blood tests.
Boster's high affinity primary antibodies are designed to capture the antigen with high affinity, because the CCT8 marker has been created in a unique way. The researcher can also ask more questions using high-affinity antibodies. This allows researchers to get better answers and more context data. Boster has all the answers, no matter if you're searching for antibodies to detect antigens or looking to find specific proteins.
Many species raise secondary antibodies. Common secondary antibodies can also be raised in chickens and rabbits. A specific species must be used to produce secondary antibodies from a single primary antibody. However, if the primary antibodies were raised in a specific animal species, it is essential to use an Anti-rabbit secondary antibody as a substitute.
Two or more primary antibody can be used to demonstrate the same antigens from different tissues. The primary antibodies must not be blocked by the pigments used for visualization. To selectively visualize both antigens, optical filter combinations are possible. It is important that primary-secondary antibodies pairs do not cross-react, or interact with antigens contained in sequential layers.
For high-affinity primary antibodies, one should select a company that specializes in producing them. These companies usually provide antibodies for hemostasis and diagnostics. They also supply immune depleted plasmas. Agrisera is a company that provides validated marker antibodies for plant containers and Rubisco quantitation methods. A large range of products complements the company's expertise and knowledge in the field of avian antibody research.
Traditional chromogenic immunohistochemistry relies on the production and maintenance of monoclonal as well as polyclonal antibody in different species. The CCT8 marker is crucial in this method. Fluorescent mIHC can detect multiple markers simultaneously. The method also enables better understanding of the relationship between different markers and antibodies.
PMID: 8590283 by Yamazaki M., et al. Nucleotide sequence surrounding the locus marker D21S246 on human chromosome 21.
PMID: 7890169 by Kubota H., et al. The eighth Cct gene, Cctq, encoding the theta subunit of the cytosolic chaperonin containing TCP-1.