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2 Citations 1 Q&As
2 Citations
1 Citations
Facts about G1/S-specific cyclin-E2.
Human | |
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Gene Name: | CCNE2 |
Uniprot: | O96020 |
Entrez: | 9134 |
Belongs to: |
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cyclin family |
CCNE2; CYCE2; Cyclin E2; G1/S-specific cyclin E2; G1/S-specific cyclin-E2
Mass (kDA):
46.757 kDA
Human | |
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Location: | 8q22.1 |
Sequence: | 8; NC_000008.11 (94880224..94896671, complement) |
According to PubMed:9858585, highest levels of expression in adult testis, thymus and brain. Lower levels in placenta, spleen and colon. Consistently elevated levels in tumor- derived cells compared to non-transformed proliferating cells. According to PubMed:9840927: low levels in thymus, prostate, brain, skeletal muscle, and kidney. Elevated levels in lung. According to PubMed:9840943 highly expressed in testis, placenta, thymus and brain. In a lesser extent in small intestine and colon.
Nucleus.
PMID: 9858585 by Gudas J.M., et al. Cyclin E2, a novel G1 cyclin that binds Cdk2 and is aberrantly expressed in human cancers.
PMID: 9840927 by Lauper N., et al. Cyclin E2: a novel CDK2 partner in the late G1 and S phases of the mammalian cell cycle.
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