Cyclin-A2 Antibodies

AND CCNA2 ELISA kits, Cyclin-A2 Proteins

Many biological assays use antibodies to detect Cyclin-A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cyclin-A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cyclin-A2 antibodies...

We validate the specificity of these antibodies to Cyclin-A2 by testing them on tissues known to express CCNA2 positively and negatively. Browse below to find the CCNA2 antibody that suites your experiment. We have 8 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CCNA2 Infographic by Boster Bio

All CCNA2 Products

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Product

Figures

Specificity

Applications

Price

Anti-Cyclin A2/CCNA2 Antibody Picoband®

6 Citations 1 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # PB9424
100 μg/vial

Anti-Cyclin A Ccna2 Antibody (Monoclonal, CY-A1)

8 Citations 6 Q&As

Bovine, Human, Mouse

ICC, WB

$370
Cat # MA1032
100 μg/vial

Anti-Cyclin A CCNA2 Antibody

3 Citations

Human

IHC, WB

$629
Cat # A00700
100uL

Anti-Cyclin A2 Rabbit Monoclonal Antibody

3 Citations

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M00700-1
100 μl

Anti-Cyclin A1/A2 Rabbit Monoclonal Antibody

2 Citations

Human

IP, IHC, WB

$370
Cat # M00700
100 μl

Anti-Cyclin A2 CCNA2 Antibody

1 Citations

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A00700-2
100ul

Human Cyclin A2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTP20248
Starting from 20ug

Cyclin A2 (CCNA2) (NM_001237) Human Over-expression Lysate

Human

$628
Cat # LS000890
100 µg

CCNA2 Overview

Facts about Cyclin-A2.

CCNA2 3D structure. Source: alphafold

Cyclin-A2 (CCNA2)

Cyclin which controls both the G1/S and the G2/M transition stages of the cell cycle. Functions through the formation of particular serine/threonine protein kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 or CDK2.

The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 through the cell cycle. .

Gene Information

Human
Gene Name:	CCNA2
Uniprot:	P20248
Entrez:	890

Family

Belongs to:

cyclin family

Alternative Names

CCN1CCNAcyclin-A; CCNA; CCNA2; Cyclin A2; Cyclin-A; cyclin-A2

Molecular Weight

Mass (kDA):
48.551 kDA

Genomic Context


Human

Location:	4q27
Sequence:	4; NC_000004.12 (121816444..121823883, complement)

Subcellular Localizations

Nucleus. Cytoplasm. Exclusively nuclear during interphase (PubMed:1312467). Detected in the nucleus and the cytoplasm at prophase (PubMed:1312467). Cytoplasmic when associated with SCAPER (PubMed:17698606).

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Malignant Neoplasm Of Breast
Mammary Neoplasms
Cell Transformation, Neoplastic
Leukemia
Retinoblastoma
Adenocarcinoma
Liver Carcinoma
Malignant Paraganglionic Neoplasm
Hyperplasia
Malignant Neoplasm Of Lung

Colorectal Cancer
Myeloid Leukemia
Polyploidy
Colorectal Neoplasms
Liver Neoplasms
Lung Neoplasms
Acute Promyelocytic Leukemia

Interacting Proteins

AKT1
CDK2
CDKN1A
CDKN1B
UHRF2

Pathways

Cell Cycle
Cell Proliferation
Mitosis
S Phase
Cell Division
Cell Cycle Arrest
Regeneration
Dna Replication
Cell Growth
Localization
Rna Interference
Spermatogenesis
Hepatocyte Proliferation

Liver Regeneration
Senescence
Oncogenesis
Dna Repair
Pathogenesis
Neurogenesis
Meiosis

PTMs

Phosphorylation
Methylation
Sumoylation

Ubiquitination
Hydroxylation
Acetylation

Research Areas

Cancer
Cell Biology
Cell Cycle and Replication
Cellular Markers
Core ESC-Like Genes

Stem Cell Markers
Tumor Suppressors

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCNA2

References

PMID: 1967822 by Wang J., et al. Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma.

PMID: 8202514 by Henglein B., et al. Structure and cell cycle-regulated transcription of the human cyclin A gene.

12 Publications of Boster Cyclin-A2 Antibodies & ELISA Kits

PubMed ID: 10.1016/j.mce.2019.110697, LncRNA HCP5 promotes cell proliferation and inhibits apoptosis via miR-27a-3p/IG...
PubMed ID: 10.1016/j.cbi.2017.07.020, Synergism between thioredoxin reductase inhibitor ethaselen and sodium selenite ...
PubMed ID: 31974617, Wang S,Zhang C,Zhang X.Downregulation of long non‑coding RNA ANRIL promotes pr...
PubMed ID: 24628936, Activin A induces growth arrest through a SMAD- dependent pathway in hepatic pro...
PubMed ID: 28749992, Zhang C, Chang C, Zhao W, Gao H, Wang Q, Li D, Zhang F, Zhang S, Xu C,. PLoS One...
PubMed ID: 28932249, Zhang C, Chang C, Li D, Zhang F, Xu C. Cell Mol Biol Lett. 2017 Sep 16;22:21. do...
PubMed ID: 25918708, Wang C, Ge Q, Chen Z, Hu J, Li F, Song X, Xu H, Ye Z. Biomed Res Int. 2015;2015:...
PubMed ID: 23337938, Mao F, Wang B, Xiao Q, Xi G, Sun W, Zhang H, Ye F, Wan F, Guo D, Lei T, Chen X. ...
PubMed ID: 20878477, Lin P, Fu J, Zhao B, Lin F, Zou H, Liu L, Zhu C, Wang H, Yu X. Mol Biol Rep. 201...
PubMed ID: 24076388, Deng L, Lu Y, Zhao X, Sun Y, Shi Y, Fan H, Liu C, Zhou J, Nie Y, Wu K, Fan D, Gu...
PubMed ID: 25151579, Zhao P, Li Y, Gao G, Wang S, Yan Y, Zhan X, Liu Z, Mao Z, Chen S, Wang L. Eur J ...
PubMed ID: 24194897, Li M, Tian L, Wang L, Yao H, Zhang J, Lu J, Sun Y, Gao X, Xiao H, Liu M. Plos On...

*More publications can be found for each product on its corresponding product page