This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about C-C motif chemokine 28.
Chemotactic activity for resting CD4, CD8 T-cells and eosinophils.
Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner..
Human | |
---|---|
Gene Name: | CCL28 |
Uniprot: | Q9NRJ3 |
Entrez: | 56477 |
Belongs to: |
---|
intercrine beta (chemokine CC) family |
CCL28; chemokine (C-C motif) ligand 28; MEC; member 28; MGC71902; Protein CCK1; VIC
Mass (kDA):
14.28 kDA
Human | |
---|---|
Location: | 5p12 |
Sequence: | 5; NC_000005.10 (43356972..43412391, complement) |
Preferentially expressed by epithelial cells of diverse tissues including normal and pathological colon, salivary gland, mammary gland, trachea and rectum. Also found in prostate, spleen, thyroid, psoriasis skin and in lower levels in peripheral blood leukocytes, small intestine, Peyer patches, stomach and normal skin.
Secreted.
PMID: 10781587 by Wang W., et al. Identification of a novel chemokine (CCL28), which binds CCR10 (GPR2).
PMID: 10975800 by Pan J., et al. A novel chemokine ligand for CCR10 and CCR3 expressed by epithelial cells in mucosal tissues.