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- Table of Contents
Facts about C-C motif chemokine 25.
Binds to CCR9. Isoform 2 is an antagonist of isoform 1.
Human | |
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Gene Name: | CCL25 |
Uniprot: | O15444 |
Entrez: | 6370 |
Belongs to: |
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intercrine beta (chemokine CC) family |
C-C motif chemokine 25; CCL25; chemokine (C-C motif) ligand 25; Chemokine TECK; Ck beta-15; Ckb15; SCYA25TECKvar; small inducible cytokine subfamily A (Cys-Cys), member 25; Small-inducible cytokine A25; TECK; TECKMGC150327; thymus expressed chemokine; Thymus-expressed chemokine
Mass (kDA):
16.609 kDA
Human | |
---|---|
Location: | 19p13.2 |
Sequence: | 19; NC_000019.10 (8052318..8062663) |
Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine.
Secreted.
PMID: 9285413 by Vicari A.P., et al. TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development.
PMID: 10229797 by Zaballos A., et al. Identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK.