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, No Gclids
C-C motif chemokine 22 Antibodies
AND CCL22 ELISA kits, C-C motif chemokine 22 Proteins
Many biological assays use antibodies to detect C-C motif chemokine 22, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C-C motif chemokine 22 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C-C motif chemokine 22 antibodies...
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CCL22 Infographic by Boster Bio
All CCL22 Products
Product
Figures
Specificity
Applications
Price
Human CCL22/MDC ELISA Kit PicoKine®
7 Citations 7 Q&As
Human
ELISA
$499
Cat # EK0446
96 wells/kit, with removable strips.
Cat # EK0446
96 wells/kit, with removable strips.
Mouse CCL22/MDC ELISA Kit PicoKine®
9 Citations 8 Q&As
Mouse
ELISA
$499
Cat # EK0447
96 wells/kit, with removable strips.
Cat # EK0447
96 wells/kit, with removable strips.
Mouse
$250
Cat # PROTO88430
5ug, 20ug, 1mg
Cat # PROTO88430
5ug, 20ug, 1mg
Human
ELISA
$499
Cat # FEK0446
96 wells/kit, with removable strips.
Cat # FEK0446
96 wells/kit, with removable strips.
CCL22 Overview
Facts about C-C motif chemokine 22.
C-C motif chemokine 22 (CCL22)
May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other facets of actuated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells.
Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but doesn't have chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4.
Gene Information
| Human | |
|---|---|
| Gene Name: | CCL22 |
| Uniprot: | O00626 |
| Entrez: | 6367 |
Family
| Belongs to: |
|---|
| intercrine beta (chemokine CC) family |
Alternative Names
A-152E5.1; ABCD-1; CC chemokine STCP-1; C-C motif chemokine 22; CCL22; chemokine (C-C motif) ligand 22; DC/B-CK; Macrophage-derived chemokine; MDC; MDCStimulated T-cell chemotactic protein 1; MGC34554; SCYA22MDC(1-69); small inducible cytokine A22; small inducible cytokine subfamily A (Cys-Cys), member 22; Small-inducible cytokine A22; STCP-1; stimulated T cell chemotactic protein 1
Molecular Weight
Mass (kDA):
10.625 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16q21 |
| Sequence: | 16; NC_000016.10 (57358783..57366189) |
Tissue Specificity
Highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus. Also found in lymph node, appendix, activated monocytes, resting and activated macrophages. Lower expression in lung and spleen. Very weak expression in small intestine. In lymph node expressed in a mature subset of Langerhans' cells (CD1a+ and CD83+). Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy. Expressed in atopic dermatitis, allergic contact dermatitis skin, and psoriasis, in both the epidermis and dermis.
Subcellular Localizations
Secreted.
Diseases
- Inflammation
- Cholangiocarcinoma
- Neoplasms
- Asthma
- Dermatitis
- Dermatitis, Atopic
- Malignant Neoplasms
- Carcinoma
- Autoimmune Reaction
- Dermatologic Disorders
- Tissue Adhesions
- Lymphoma
- Allergy
Pathways
- Pathogenesis
- Secretion
- Immune Response
- Chemotaxis
- Chemokine Production
- Sensitization
- Cell Migration
- Inflammatory Response
- Cell Proliferation
- Localization
- Cell Activation
- T Cell Proliferation
- Cytokine Production
PTMs
- Phosphorylation
- Cleavage
- Oxidation
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCL22
bosterbio.com/bosterbio-gene-info-cards/CCL22
References
PMID: 9312138 by Chang M.-S., et al. Molecular cloning and functional characterization of a novel CC chemokine, stimulated T cell chemotactic protein (STCP-1) that specifically acts on activated T lymphocytes.
PMID: 9151897 by Godiska R., et al. Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells.
16 Publications of Boster C-C motif chemokine 22 Antibodies & ELISA Kits
- PubMed ID: 10.1186/s12967-016-0799-7, Fusion cytokine IL-2-GMCSF enhances anticancer immune responses through promotin...
- PubMed ID: 10.1080/08923973.2019.1680688, dl-Malic acid as a component of α-hydroxy acids: effect on 2,4-dinitrochloroben...
- PubMed ID: 10.1080/00365521.2020.1748222, Clinical features and monocyte/macrophage subsets characterization in granulomat...
- PubMed ID: 10.1038/mtna.2016.71, miR-181a Induces Macrophage Polarized to M2 Phenotype and Promotes M2 Macrophage...
- PubMed ID: 10.1016/j.omto.2021.07.014, Systemic delivery of TNF-armed myxoma virus plus immune checkpoint inhibitor eli...
- PubMed ID: 10.1016/j.jep.2021.114453, Effects of chloroform fraction of Fritillariae Thunbergii Bulbus on atopic sympt...
- PubMed ID: 10.1016/j.jep.2017.12.009, Pathway analysis of global gene expression change in dendritic cells induced by ...
- PubMed ID: 10.1016/j.intimp.2019.105955, Activation of RAW264.7 macrophages by active fraction of Albizia julibrissin sap...
- PubMed ID: 10.1016/j.ijrobp.2020.05.001, Radiation-Enhanced Expression of CCL22 in Nasopharyngeal Carcinoma is Associated...
- PubMed ID: 10.1016/j.ijbiomac.2021.03.006, Structural characteristics and immunopotentiation activity of two polysaccharide...
- PubMed ID: 33676979, He Y, Peng H, Zhang H, Liu Y, Sun H. Structural characteristics and immunopotent...
- PubMed ID: 32492489, Cao, Y., Cao, W., Qiu, Y., Zhou, Y., Guo, Q., Gao, Y., & Lu, N. (2020). Oroxylin...
- PubMed ID: 27673564, miR-181a Induces Macrophage Polarized to M2 Phenotype and Promotes M2 Macrophage...
- PubMed ID: 26850448, Fusion cytokine IL-2-GMCSF enhances anticancer immune responses through promotin...
- PubMed ID: 29247698, Du, J., Chen, X., Wang, C., & Sun, H. (2017). Pathway analysis of global gene ex...
- PubMed ID: 22082565, Chen D, Hu Q, Mao C, Jiao Z, Wang S, Yu L, Xu Y, Dai D, Yin L, Xu H. Cell Immuno...
*More publications can be found for each product on its corresponding product page