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C-C motif chemokine 21 Antibodies
AND CCL21 ELISA kits, C-C motif chemokine 21 Proteins
Many biological assays use antibodies to detect C-C motif chemokine 21, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C-C motif chemokine 21 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C-C motif chemokine 21 antibodies...
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CCL21 Infographic by Boster Bio
All CCL21 Products
Product
Figures
Specificity
Applications
Price
Human CCL21 / 6Ckine / Exodus 2 ELISA Kit PicoKine®
3 Citations 10 Q&As
Human
ELISA
$499
Cat # EK0555
96 wells/kit, with removable strips.
Cat # EK0555
96 wells/kit, with removable strips.
Human
ELISA
$500
Cat # EZ0555
For 5 plates, 96 wells each
Cat # EZ0555
For 5 plates, 96 wells each
Human
ELISA
$499
Cat # FEK0555
96 wells/kit, with removable strips.
Cat # FEK0555
96 wells/kit, with removable strips.
CCL21 Overview
Facts about C-C motif chemokine 21.
C-C motif chemokine 21 (CCL21)
Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils.
Shows preferential action towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs.
Gene Information
| Human | |
|---|---|
| Gene Name: | CCL21 |
| Uniprot: | O00585 |
| Entrez: | 6366 |
Family
| Belongs to: |
|---|
| intercrine beta (chemokine CC) family |
Alternative Names
6Ckine; 6CkineSmall-inducible cytokine A21; Beta-chemokine exodus-2; CCL21; chemokine (C-C motif) ligand 21; CKb9; exodus-2; member 21; SCYA21; SCYA21MGC34555; secondary lymphoid tissue chemokine; SLC; SLCSecondary lymphoid-tissue chemokine; TCA-4
Molecular Weight
Mass (kDA):
14.646 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9p13.3 |
| Sequence: | 9; NC_000009.12 (34709005..34710136, complement) |
Tissue Specificity
Highly expressed in high endothelial venules of lymph nodes, spleen and appendix. Intermediate levels found in small intestine, thyroid gland and trachea. Low level expression in thymus, bone marrow, liver, and pancreas. Also found in tonsil, fetal heart and fetal spleen.
Subcellular Localizations
Secreted.
Diseases
- Neoplasms
- Inflammation
- Malignant Neoplasms
- Tissue Adhesions
- Cholangiocarcinoma
- Neoplasm Metastasis
- Autoimmune Reaction
- Rheumatoid Arthritis
- Arthritis
- Carcinoma
- Melanoma
- Cell Invasion
- Lymphatic Metastasis
Interacting Proteins
- CCL13
- CCL17
- CCL26
- CCL28
- CCL5
- CXCL10
- CXCL12
- CXCL14
- CXCL9
- PF4
Pathways
- Chemotaxis
- Cell Migration
- Immune Response
- Pathogenesis
- Secretion
- Localization
- Cell Adhesion
- Cell Proliferation
- Lymphocyte Migration
- Cell Activation
- Cytokine Production
- Dendritic Cell Migration
- T Cell Migration
PTMs
- Phosphorylation
- Reduction
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCL21
bosterbio.com/bosterbio-gene-info-cards/CCL21
References
PMID: 9235955 by Nagira M., et al. Molecular cloning of a novel human CC chemokine secondary lymphoid- tissue chemokine that is a potent chemoattractant for lymphocytes and mapped to chromosome 9p13.
PMID: 9257816 by Hedrick J.A., et al. Identification and characterization of a novel beta chemokine containing six conserved cysteines.
3 Publications of Boster C-C motif chemokine 21 Antibodies & ELISA Kits
- PubMed ID: 10.3390/genes11111309, Lymphatic Metastasis of NSCLC Involves Chemotaxis Effects of Lymphatic Endotheli...
- PubMed ID: 33158173, Zhang S, Wang H, Xu Z, Bai Y, Xu L. Lymphatic Metastasis of NSCLC Involves Chemo...
- PubMed ID: 25230206, Low-dose paclitaxel improves the therapeutic efficacy of recombinant adenovirus ...
*More publications can be found for each product on its corresponding product page