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- Table of Contents
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C-C motif chemokine 18 Antibodies
AND CCL18 ELISA kits, C-C motif chemokine 18 Proteins
Many biological assays use antibodies to detect C-C motif chemokine 18, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C-C motif chemokine 18 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C-C motif chemokine 18 antibodies...
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CCL18 Infographic by Boster Bio
All CCL18 Products
Product
Figures
Specificity
Applications
Price
Human CCL18/PARC ELISA Kit PicoKine®
2 Citations 4 Q&As
Human
ELISA
$499
Cat # EK0686
96 wells/kit, with removable strips.
Cat # EK0686
96 wells/kit, with removable strips.
Anti-Macrophage Inflammatory Protein 4/CCL18 Antibody Picoband®
1 Citations 4 Q&As
Human
ELISA, WB
$370
Cat # PB9023
100 μg/vial
Cat # PB9023
100 μg/vial
Human
ELISA
$500
Cat # EZ0686
For 5 plates, 96 wells each
Cat # EZ0686
For 5 plates, 96 wells each
$1249
Cat # PROTP55774
20 µg
Cat # PROTP55774
20 µg
Human
$628
Cat # LS006362
100 µg
Cat # LS006362
100 µg
Human
ELISA
$499
Cat # FEK0686
96 wells/kit, with removable strips.
Cat # FEK0686
96 wells/kit, with removable strips.
CCL18 Overview
Facts about C-C motif chemokine 18.
C-C motif chemokine 18 (CCL18)
Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration to B-cell follicles in lymph nodes.
Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CCL18 |
| Uniprot: | P55774 |
| Entrez: | 6362 |
Family
| Belongs to: |
|---|
| intercrine beta (chemokine CC) family |
Alternative Names
Alternative macrophage activation-associated CC chemokine 1; AMAC-1; AMAC1CC chemokine ligand 18; AMAC-1Small-inducible cytokine A18; CCL18; chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated); CKb7; DC-CK1; DC-CK1CC chemokine PARC; DCCK1Macrophage inflammatory protein 4; Dendritic cell chemokine 1; MIP4; MIP-4; MIP-4C-C motif chemokine 18; PARC; PARCPulmonary and activation-regulated chemokine; SCYA18chemokine (C-C), dendritic; small inducible cytokine A18; small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary andactivation-regulated
Molecular Weight
Mass (kDA):
9.849 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q12 |
| Sequence: | 17; NC_000017.11 (36064272..36072032) |
Tissue Specificity
Expressed at high levels in lung, lymph nodes, placenta, bone marrow, dendritic cells present in germinal centers and T-cell areas of secondary lymphoid organs and macrophages derived from peripheral blood monocytes. Not expressed by peripheral blood monocytes and a monocyte-to-macrophage differentiation is a prerequisite for expression. Expressed in synovial fluids from patients with rheumatoid and septic arthritis and in ovarian carcinoma ascitic fluid.
Subcellular Localizations
Secreted.
Diseases
- Inflammation
- Cholangiocarcinoma
- Malignant Neoplasms
- Neoplasms
- Gaucher Disease
- Fibrosis
- Dermatitis, Atopic
- Dermatitis
- Pulmonary Fibrosis
- Lung Diseases
- Arthritis
- Rheumatoid Arthritis
- Neoplasm Metastasis
Interacting Proteins
- PITPNM3
Pathways
- Pathogenesis
- Immune Response
- Secretion
- Angiogenesis
- Chemotaxis
- Macrophage Activation
- Chemokine Production
- Inflammatory Response
- Cytokine Production
- Cell Activation
- Fibroblast Proliferation
- Transport
- Hypersensitivity
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCL18
bosterbio.com/bosterbio-gene-info-cards/CCL18
References
PMID: 9233607 by Hieshima K., et al. A novel human CC chemokine PARC that is most homologous to macrophage-inflammatory protein-1 alpha/LD78 alpha and chemotactic for T lymphocytes, but not for monocytes.
PMID: 9570561 by Kodelja V., et al. Alternative macrophage activation-associated CC-chemokine-1, a novel structural homologue of macrophage inflammatory protein-1 alpha with a Th2-associated expression pattern.
3 Publications of Boster C-C motif chemokine 18 Antibodies & ELISA Kits
- PubMed ID: 10.1111/jcmm.15360, Natural antiviral compound silvestrol modulates human monocyte‐derived macroph...
- PubMed ID: 10.1007/s00109-020-02024-4, The immunomodulatory potential of the arylmethylaminosteroid sc1o
- PubMed ID: 33330947, Blum L, Ulshöfer T, Henke M, Krieg R, Berneburg I, Geisslinger G, Becker K, Par...
*More publications can be found for each product on its corresponding product page