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C-C motif chemokine 14 Antibodies
AND CCL14 ELISA kits, C-C motif chemokine 14 Proteins
Many biological assays use antibodies to detect C-C motif chemokine 14, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C-C motif chemokine 14 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C-C motif chemokine 14 antibodies...
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CCL14 Infographic by Boster Bio
All CCL14 Products
Product
Figures
Specificity
Applications
Price
Human CCL14/HCC-1 ELISA Kit PicoKine®
1 Citations 9 Q&As
Human
ELISA
$499
Cat # EK1123
96 wells/kit, with removable strips.
Cat # EK1123
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # FEK1123
96 wells/kit, with removable strips.
Cat # FEK1123
96 wells/kit, with removable strips.
Human
ELISA
$500
Cat # EZ1123
For 5 plates, 96 wells each, reagents only, plates are not included
Cat # EZ1123
For 5 plates, 96 wells each, reagents only, plates are not included
CCL14 Overview
Facts about C-C motif chemokine 14.
C-C motif chemokine 14 (CCL14)
Has weak activities on human monocytes and acts through receptors that also recognize MIP-1 alpha. It induces intracellular Ca(2+) changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and is dormant on T-lymphocytes, neutrophils, and eosinophil leukocytes.
Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes, eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5.
Gene Information
| Human | |
|---|---|
| Gene Name: | CCL14 |
| Uniprot: | Q16627 |
| Entrez: | 6358 |
Family
| Belongs to: |
|---|
| intercrine beta (chemokine CC) family |
Alternative Names
C-C motif chemokine 14; CCL14; chemokine (C-C motif) ligand 14; Chemokine CC-1/CC-3; chemokine CC-3; CKB1; FLJ16015; HCC-1; HCC-1(1-74); HCC-1/HCC-3; HCC-3; hemofiltrate CC chemokine 1; MCIF; member 14; NCC2CC-1; NCC-2CKb1; new CC chemokine 2; SCYA14CC-3; Small-inducible cytokine A14
Molecular Weight
Mass (kDA):
10.678 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q12 |
| Sequence: | 17; NC_000017.11 (35983288..35986729, complement) |
Tissue Specificity
Expressed constitutively in several normal tissues: spleen, liver, skeletal and heart muscle, gut, and bone marrow, present at high concentrations (1-80 nM) in plasma.
Subcellular Localizations
Secreted.
Diseases
- Cholangiocarcinoma
- Neoplasms
- Malignant Neoplasms
- Inflammation
- Hiv Infections
- Cell Invasion
- Neoplasm Metastasis
- Tumor Angiogenesis
- Endometrial Polyp
- Leukemia
- Acquired Immunodeficiency Syndrome
- Immunologic Deficiency Syndromes
- Liver Carcinoma
Pathways
- Chemotaxis
- Cell Migration
- Embryo Implantation
- Angiogenesis
- Pathogenesis
- Immune Response
- Leukocyte Migration
- Cell Proliferation
- Induction Of Apoptosis
- Proteolysis
- Dna Repair
- Adaptive Immune Response
- Lymphocyte Migration
PTMs
- Cleavage
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCL14
bosterbio.com/bosterbio-gene-info-cards/CCL14
References
PMID: 8551235 by Schulz-Knappe P., et al. HCC-1, a novel chemokine from human plasma.
PMID: 9600961 by Pardigol A., et al. HCC-2, a human chemokine: gene structure, expression pattern, and biological activity.
1 Publications of Boster C-C motif chemokine 14 Antibodies & ELISA Kits
- PubMed ID: 20880063, Guo H, Nan K, Hu T, Meng J, Hui W, Zhang X, Qin H, Sui C. Hepatol Res. 2010 Nov;...
*More publications can be found for each product on its corresponding product page