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- Table of Contents
Facts about Coiled-coil domain-containing protein 80.
.
Rat | |
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Gene Name: | Ccdc80 |
Uniprot: | Q6QD51 |
Entrez: | 64387 |
Belongs to: |
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CCDC80 family |
CCDC80; coiled-coil domain containing 80; down-regulated by oncogenes protein 1; DRO1; SSG1; Steroid-sensitive protein 1; URB
Mass (kDA):
107.691 kDA
Rat | |
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Location: | 11q21 |
Sequence: | 11; |
Isoform 2 is expressed in uterus, liver, lung, spleen, kidney, heart, bladder, skeletal muscle and brain (at protein level). Isoform 2 is expressed very low in mammary gland and intestine (at protein level). Isoform 2 is expressed in lactating mammary glands and mammary tumors (at protein level). Ubiquitous (isoform 1). Isoform 2 is expressed in ovary, uterus, mammary glands, liver, lung, spleen, kidney, heart, bladder, intestine, skeletal muscle and brain.
PMID: 11356689 by Marcantonio D., et al. Cloning and characterization of a novel gene that is regulated by estrogen and is associated with mammary gland carcinogenesis.
PMID: 15563452 by Bommer G.T., et al. DRO1, a gene down-regulated by oncogenes, mediates growth inhibition in colon and pancreatic cancer cells.