Protein chibby homolog 1 Antibodies

AND CBY1 ELISA kits, Protein chibby homolog 1 Proteins

Many biological assays use antibodies to detect Protein chibby homolog 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein chibby homolog 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein chibby homolog 1 antibodies...

We validate the specificity of these antibodies to Protein chibby homolog 1 by testing them on tissues known to express CBY1 positively and negatively. Browse below to find the CBY1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CBY1 Infographic by Boster Bio

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PGEA1 (CBY1) (NM_015373) Human Recombinant Protein

$813
Cat # PROTQ9Y3M2
20 µg

CBY1 Overview

Facts about Protein chibby homolog 1.

CBY1 3D structure. Source: alphafold

Protein chibby homolog 1 (CBY1)

Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a part in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins.

Promotes adipocyte and cardiomyocyte differentiation. .

Gene Information

Human
Gene Name:	CBY1
Uniprot:	Q9Y3M2
Entrez:	25776

Family

Belongs to:

chibby family

Alternative Names

arb1; ARPP-binding protein; C22orf2chromosome 22 open reading frame 2; Cby; CBYgolgi and endoplasmic reticulum associated 1; chibby homolog 1 (Drosophila); coiled-coil protein PIGEA-14; Cytosolic leucine-rich protein; HS508I15A; PGEA1; PIGEA-14Chibby; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; polycystin-2 interactor, Golgi- and endoplasmic reticulum-associated protein; protein chibby homolog 1

Molecular Weight

Mass (kDA):
14.47 kDA

Genomic Context


Human

Location:	22q13.1
Sequence:	22; NC_000022.11 (38656653..38673850)

Tissue Specificity

Widely expressed. Expressed at higher levels in heart, skeletal muscle, kidney and placenta. Also found in brain, lung, liver and testis. Significantly down-regulated in thyroid and metastatic uterine tumors.

Subcellular Localizations

Nucleus speckle. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Golgi apparatus. Golgi apparatus, trans-Golgi network.