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Caspase-9 Antibodies
AND CASP9 ELISA kits, Caspase-9 Proteins
Many biological assays use antibodies to detect Caspase-9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Caspase-9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Caspase-9 antibodies...
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CASP9 Infographic by Boster Bio
All CASP9 Products
Product
Figures
Specificity
Applications
Price
Anti-Caspase 9/CASP9 Antibody Picoband®
19 Citations 5 Q&As
Human
IHC, WB
$370
Cat # PA1595
100 μg/vial
Cat # PA1595
100 μg/vial
Anti-Caspase-9 CASP9 Antibody
4 Citations 14 Q&As
Bovine, Chicken, Dog, Guinea pig, Human, Monkey, Mouse, Rat, Sheep
WB
$474
Cat # A00080
100μg/vial
Cat # A00080
100μg/vial
Anti-Caspase-9 CASP9 Rabbit Monoclonal Antibody
3 Citations 15 Q&As
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00080-3
100 μl
Cat # M00080-3
100 μl
Anti-Caspase-9 CASP9 Rabbit Monoclonal Antibody
4 Citations 14 Q&As
Human, Mouse
IP, IF, IHC, ICC, WB
$370
Cat # M00080
100 μl
Cat # M00080
100 μl
Anti-pro Caspase 9 CASP9 Rabbit Monoclonal Antibody
3 Citations 14 Q&As
Human
Flow Cytometry, IHC, WB
$370
Cat # M00080-1
100 μl
Cat # M00080-1
100 μl
Anti-cleaved Caspase-9 CASP9 Rabbit Monoclonal Antibody
6 Citations 15 Q&As
Human, Mouse
IP, WB
$370
Cat # M00080-2
100 μl
Cat # M00080-2
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1089
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1089
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC1977
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1977
1 kit, containing two 96-well plates and all necessary reagents
Human
ELISA
$540
Cat # EKC2224
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2224
1 kit, containing two 96-well plates and all necessary reagents
Human
ELISA
$540
Cat # EKC2225
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2225
1 kit, containing two 96-well plates and all necessary reagents
Human
ELISA
$540
Cat # EKC2226
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2226
1 kit, containing two 96-well plates and all necessary reagents
Anti-Caspase-9 CASP9 Antibody
1 Citations
Human, Mouse
ELISA, IP, IF, ICC, WB
$449
Cat # A00080-1
0.1 mg
Cat # A00080-1
0.1 mg
Human, Mouse, Rat
ELISA, IHC, WB
$380
Cat # A00080T125-1
100ul
Cat # A00080T125-1
100ul
Anti-Caspase 9 CASP9 Monoclonal Antibody
1 Citations
Chicken, Human, Mouse, Rat
IP, IF, IHC, WB
$380
Cat # M00080-5
100ul
Cat # M00080-5
100ul
Anti-Caspase-9 p35/Casp9 Antibody Picoband®
2 Citations
Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00080-4
100 μg/vial
Cat # A00080-4
100 μg/vial
Anti-Caspase-9/CASP9 Antibody Picoband®
1 Citations
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00080-5
100 μg/vial
Cat # A00080-5
100 μg/vial
Human
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00080-6
100 μg/vial
Cat # A00080-6
100 μg/vial
Anti-Caspase-9/Casp9 Antibody Picoband®
10 Citations
Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00080-7
100 μg/vial
Cat # A00080-7
100 μg/vial
Anti-Caspase-9/CASP9 Antibody Picoband®
10 Citations
Human
ELISA, Flow Cytometry, WB
$370
Cat # A00080-8
100 μg/vial
Cat # A00080-8
100 μg/vial
CASP9 Overview
Facts about Caspase-9.
Caspase-9 (CASP9)
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3.
Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent method. Proteolytically cleaves poly(ADP- ribose) polymerase (PARP).
Gene Information
| Human | |
|---|---|
| Gene Name: | CASP9 |
| Uniprot: | P55211 |
| Entrez: | 842 |
Family
| Belongs to: |
|---|
| peptidase C14A family |
Alternative Names
APAF-3APAF3; apoptotic protease activating factor 3; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; CASP9; CASP-9; caspase 9, apoptosis-related cysteine peptidase; Caspase9; Caspase-9; EC 3.4.22.62; ICE-LAP6CASPASE-9c; ICE-like apoptotic protease 6; MCH6apoptosis-related cysteine protease
Molecular Weight
Mass (kDA):
46.281 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p36.21 |
| Sequence: | 1; NC_000001.11 (15491401..15524912, complement) |
Tissue Specificity
Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Leukemia
- Mammary Neoplasms
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Breast
- Lymphoma
- Malignant Tumor Of Colon
- Adenocarcinoma
- Neuroblastoma
- Ischemia
- Colonic Neoplasms
Interacting Proteins
- APAF1
- BIRC2
- BIRC3
- BIRC5
- BIRC7
- CASP3
- DCC
- ILK
- XIAP
Pathways
- Cell Death
- Induction Of Apoptosis
- Cell Cycle
- Programmed Cell Death
- Cell Proliferation
- Pathogenesis
- Release Of Cytochrome C From Mitochondria
- Cell Growth
- Apoptotic Process
- Localization
- Cell Cycle Arrest
- Proteolysis
- Sensitization
PTMs
- Cleavage
- Phosphorylation
- Methylation
- Dephosphorylation
- Acetylation
- Ubiquitination
- Reduction
- Oxidation
- Nitrosylation
- Demethylation
Research Areas
- Alzheimers Research
- Apoptosis
- Cancer
- Caspases
- Cell Biology
- Neurodegeneration
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CASP9
bosterbio.com/bosterbio-gene-info-cards/CASP9
References
PMID: 8663294 by Duan H., et al. ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B.
PMID: 8900201 by Srinivasula S.M., et al. The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32.
37 Publications of Boster Caspase-9 Antibodies & ELISA Kits
- PubMed ID: 10.3892/or.2011.1163, GROβ and its downstream effector EGR1 regulate cisplatin-induced apoptosis in W...
- PubMed ID: 10.3892/ol.2013.1449, Effects of matrine on the proliferation of HT29 human colon cancer cells and its...
- PubMed ID: 10.3892/mmr.2014.2859, HIF‑1 signaling pathway involving iNOS, COX‑2 and caspase‑9 mediates the n...
- PubMed ID: 10.3892/ijo.2015.3039, Autophagy is involved in recombinant Newcastle disease virus (rL-RVG)-induced ce...
- PubMed ID: 10.3389/fphar.2021.609702, Anti-Myocardial Ischemia Reperfusion Injury Mechanism of Dried Ginger-Aconite De...
- PubMed ID: 10.1248/bpb.b13-00794, Involvement of substance P/neurokinin-1 receptor in the analgesic and anticancer...
- PubMed ID: 10.1186/s12985-017-0852-z, Recombinant Newcastle disease virus rL-RVG enhances the apoptosis and inhibits t...
- PubMed ID: 10.1186/1556-276X-9-319, In vivo and in vitro evaluation of the cytotoxic effects of Photosan-loaded holl...
- PubMed ID: 10.1111/dth.14720, CD4+T cells apoptosis and conversion of Th1/Th2‐type cytokines promote the pro...
- PubMed ID: 10.1080/15376516.2017.1333553, Rotenone induces nephrotoxicity in rats: oxidative damage and apoptosis
- PubMed ID: 10.1039/C5TB00514K, Design of magnetic nanoparticles for hepatocellular carcinoma treatment using th...
- PubMed ID: 10.1016/j.ijpharm.2016.08.037, Vitamin E TPGS modified liposomes enhance cellular uptake and targeted delivery ...
- PubMed ID: 10.1016/j.bbrc.2005.03.182, Inhibition of the PI3K pathway sensitizes fludarabine-induced apoptosis in human...
- PubMed ID: 10.1002/ptr.5241, Isoflavones Extracted from Chickpea Cicer arietinum L. Sprouts Induce Mitochondr...
- PubMed ID: -, Xuening Pang,Xiang Gao,Feng Liu,Yuhuan Jiang,Mingji Wang,Qun Li,Zichao Li,Xantho...
- PubMed ID: 33654381, Xu Y,Chen W,Chen Z,Huang M,Yang F,Zhang Y.Mechanism of Action of Xiaoyao San in ...
- PubMed ID: 32802118, Li QY,Hou CZ,Yang LP,Chu XL,Wang Y,Zhang P,Zhao Y. Study on the Mechanism of Gin...
- PubMed ID: 33284899, Yue W,Cunlin G,Lu H,Yuanqing Z,Yanjun T,Qiong W. Neuroprotective effect of inter...
- PubMed ID: 27915342, In Vitro Effects of HAS-2 Gene Silencing on the Proliferation and Apoptosis of t...
- PubMed ID: 28197193, Chinese herbal medicine Yougui Pill reduces exogenous glucocorticoid-induced apo...
- PubMed ID: 25024681, In vivo?and?in vitro?evaluation of the cytotoxic effects of Photosan-loaded holl...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page