CAPZB Antibodies

AND CAPZB ELISA kits, CAPZB Proteins

Many biological assays use antibodies to detect CAPZB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CAPZB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CAPZB antibodies...

We validate the specificity of these antibodies to CAPZB by testing them on tissues known to express CAPZB positively and negatively. Browse below to find the CAPZB antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CAPZB Infographic by Boster Bio

All CAPZB Products

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Product

Figures

Specificity

Applications

Price

Anti-CAPZB Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A05623
100ul

CAPZB (NM_004930) Human Over-expression Lysate

Human

$628
Cat # LS000832
100 µg

CAPZB Overview

Facts about F-actin-capping protein subunit beta.

CAPZB 3D structure. Source: alphafold

F-actin-capping protein subunit beta (CAPZB)

F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.

Plays a role in the regulation of cell morphology and cytoskeletal organization. .

Gene Information

Human
Gene Name:	CAPZB
Uniprot:	P47756
Entrez:	832

Family

Belongs to:

F-actin-capping protein beta subunit family

Alternative Names

Cap Z; CAPB; CAPPB; capping protein (actin filament) muscle Z-line, beta; CapZ beta; CAPZ; F-actin capping protein beta subunit; F-actin-capping protein subunit beta; MGC104401; MGC129749; MGC129750

Molecular Weight

Mass (kDA):
31.35 kDA

Genomic Context


Human

Location:	1p36.13
Sequence:	1; NC_000001.11 (19338775..19485539, complement)

Subcellular Localizations

Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere.

Diseases

Thyroid Diseases
Hypothyroidism
Spinal Cord Injuries
Male Infertility
Schizophrenia
Muscular Atrophy
Hypoxia
Atrophy
Infertility
Autoimmune Diseases
Dystrophy

Cataract
Goiter
Autoimmune Reaction
Inflammation
Celiac Disease
Tissue Damage

Pathways

Localization
Locomotion
Aging
Muscle Atrophy
Secretion

PTMs

Phosphorylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CAPZB

References

PMID: 7665558 by Barron-Casella E.A., et al. Sequence analysis and chromosomal localization of human Cap Z. Conserved residues within the actin-binding domain may link Cap Z to gelsolin/severin and profilin protein families.

PMID: 15850461 by Eyers C.E., et al. The phosphorylation of CapZ-interacting protein (CapZIP) by stress- activated protein kinases triggers its dissociation from CapZ.