CAPZA2 Antibodies

AND CAPZA2 ELISA kits, CAPZA2 Proteins

Many biological assays use antibodies to detect CAPZA2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CAPZA2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CAPZA2 antibodies...

We validate the specificity of these antibodies to CAPZA2 by testing them on tissues known to express CAPZA2 positively and negatively. Browse below to find the CAPZA2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CAPZA2 Infographic by Boster Bio

All CAPZA2 Products

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Product

Figures

Specificity

Applications

Price

Human CAPZA2 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTP47755
Starting from 20ug

CAPZA2 (NM_006136) Human Over-expression Lysate

Human

$628
Cat # LS000830
100 µg

CAPZA2 Overview

Facts about F-actin-capping protein subunit alpha-2.

CAPZA2 3D structure. Source: alphafold

F-actin-capping protein subunit alpha-2 (CAPZA2)

F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.

Gene Information

Human
Gene Name:	CAPZA2
Uniprot:	P47755
Entrez:	830

Family

Belongs to:

F-actin-capping protein alpha subunit family

Alternative Names

CAPPA2CAPZ; capping protein (actin filament) muscle Z-line, alpha 2; CapZ alpha-2; F-actin capping protein alpha-2 subunit; F-actin-capping protein subunit alpha-2

Molecular Weight

Mass (kDA):
32.949 kDA

Genomic Context


Human

Location:	7q31.2
Sequence:	7; NC_000007.14 (116862587..116922049)

Diseases

Neoplasms
Malignant Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms
Cell Transformation, Neoplastic
Prostatic Neoplasms
Obesity
Glioblastoma

Glioma
Malignant Paraganglionic Neoplasm
Malignant Glioma

Pathways

Localization
Cell Motility

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CAPZA2

References

PMID: 7665558 by Barron-Casella E.A., et al. Sequence analysis and chromosomal localization of human Cap Z. Conserved residues within the actin-binding domain may link Cap Z to gelsolin/severin and profilin protein families.

PMID: 9331217 by Hart M.C., et al. Vertebrates have conserved capping protein alpha isoforms with specific expression patterns.